| Long name: |
2, 2) Monoclonal Antibody, MBD3 (995CT3 |
| Also known as: |
2, 2) Monoclonal Antibody, MBD3 (995CT3 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MBD3 |
| Specificity: |
This is a highly specific antibody against MBD3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
2, 2, 995CT3 |
| Source: |
Purified His-tagged MBD3 protein was used to produced this monoclonal antibody |
| Gene ID number: |
53615 |
| Swiss Prot: |
O95983 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro), Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175), Does not bind to DNA by itself (PubMed:12124384), Recruits histone deacetylases and DNA methyltransferases, Acts as transcriptional repressor and plays a role in gene silencing |
| Purification method: |
This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MBD3, Methyl-CpG-binding protein MBD3, Methyl-CpG-binding domain protein 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
2, 2) Monoclonal, MBD3 (995CT3 |
| Short name: |
2, 2) Monoclonal Antibody, MBD3 (995CT3 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
2, 2) monoclonal (Antibody to), MBD3 (995CT3 |
| Alternative technique: |
antibodies |
| Identity: |
6918 |
| Gene: |
MBD3 |
More about : MBD3 |
| Long gene name: |
methyl-CpG binding domain protein 3 |
| Locus: |
19p13 |
| Discovery year: |
1999-01-11 |
| GenBank acession: |
AF072247 |
| Entrez gene record: |
53615 |
| Pubmed identfication: |
9774669 10441743 |
| RefSeq identity: |
NM_003926 |
| Classification: |
NuRD complex Methyl-CpG binding domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180081 |