| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human ZAP70 |
| known also as: |
Rabbit PAb (IgG) to Human ZAP70 |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens ZAP70 |
| known also as: |
ZAP70 |
| known also as: |
70 kDa zeta-associated protein, Human ZAP70, SRK, STCD, STD, Syk-related tyrosine kinase, TZK, Tyrosine-protein kinase ZAP-70, ZAP-70, ZAP70, Zeta-associated protein 70, Anti-ZAP70 Antibody (aa460-509) IHC-plus |
| Other names: |
70 kDa zeta-associated protein, 70 kDa zeta-chain associated protein, 70 kDa zeta-chain associated protein, 70kD, Syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, tyrosine-protein kinase ZAP-70 isoform 1 |
| Gene name: |
ZAP70 |
| Other gene names: |
SRK, SRK, STCD, STD, TZK, ZAP-70, ZAP70, ZAP70 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
ZAP-70 (Ab-493) Antibody detects endogenous levels of total ZAP-70 protein |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 150 mM sodium chloride, 50% glycerol, Ca2+), pH 7, 02% sodium azide, 4, PBS (without Mg2+ |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
for up to one year, Store productone should be stored at -20 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb ZAP70 |
| Short name: |
PAb (IgG) ZAP70 |
| Technique: |
IgGs, IgG |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
sapiens zeta-chain (TCR) associated protein kinase 70kDa, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
immunoglobulins |
| Alternative to gene target: |
Cell surfaces, SRK and STCD and STD and TZK and ZAP-70, ZAP70 and IDBG-62509 and ENSG00000115085 and 7535, ZAP70 and IDBG-629842 and ENSBTAG00000005892 and 504509, Zap70 and IDBG-145089 and ENSMUSG00000026117 and 22637, this GO :0001772 and immunological synapse and cellular component this GO :0001784 and phosphotyrosine binding and molecular function this GO :0002250 and adaptive immune response and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006955 and immune response and biological process this GO :0016772 and transferase activity, this GO :0001784 : phosphotyrosine binding, this GO :0001784 : phosphotyrosine binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042113 and B cell activation and biological process this GO :0043366 and beta selection and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045061 and thymic T cell selection and biological process this GO :0045121 and membrane raft and cellular component this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0070489 and T cell aggregation and biological process this GO :0072678 and T cell migration and biological process, zeta-chain (TCR) associated protein kinase 70kDa |
| Identity: |
12858 |
| Gene: |
ZAP70 |
More about : ZAP70 |
| Long gene name: |
zeta chain of T-cell receptor associated protein kinase 70 |
| Synonyms gene: |
SRK |
| Synonyms gene name: |
zeta-chain (TCR) associated protein kinase (70 kD) zeta-chain (TCR) associated protein kinase 70kDa zeta chain of T cell receptor associated protein kinase 70kDa zeta chain of T cell receptor associated protein kinase 70 |
| Synonyms: |
ZAP-70 STD |
| Synonyms name: |
tyrosine-protein kinase ZAP-70 |
| Locus: |
2q11, 2 |
| Discovery year: |
1995-05-16 |
| GenBank acession: |
L05148 |
| Entrez gene record: |
7535 |
| Pubmed identfication: |
1423621 |
| RefSeq identity: |
NM_001079 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000153060 |
| Locus Specific Databases: |
ZAP70base: Mutation registry for autosomal recessive ZAP70 immunodeficiency LRG_126 |