| Long name: |
12, 5) Monoclonal Antibody, MME/CD10 (307CT12 |
| Also known as: |
12, 5) Monoclonal Antibody, MME/CD10 (307CT12 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MME/CD10 |
| Specificity: |
This is a highly specific antibody against MME/CD10 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
5, 12, 307CT12 |
| Source: |
This MME/CD10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from human MME/CD10 |
| Gene ID number: |
4311 |
| Swiss Prot: |
P08473 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100~250) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Able to cleave angiotensin-1, Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991), Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573), Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276), PubMed:8168535), angiotensin-2 and angiotensin 1-9 (PubMed:15283675), but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, Thermolysin-like specificity |
| Purification method: |
This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Atriopeptidase, CALLA, CD10, CMT2T, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24, SFE, Skin fibroblast elastase, 11, NEP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
12, 5) Monoclonal, MME/CD10 (307CT12 |
| Short name: |
12, 5) Monoclonal Antibody, MME/CD10 (307CT12 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
12, 5) monoclonal (Antibody to), MME/CD10 (307CT12 |
| Alternative technique: |
antibodies |
| Identity: |
7154 |
| Gene: |
MME |
More about : MME |
| Long gene name: |
membrane metalloendopeptidase |
| Synonyms: |
CALLA CD10 NEP |
| Synonyms name: |
neutral endopeptidase enkephalinase neprilysin |
| Locus: |
3q25, 2 |
| Discovery year: |
1989-05-15 |
| Entrez gene record: |
4311 |
| RefSeq identity: |
NM_000902 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000158455 |