| Long name: |
p21 (AF9D10) Monoclonal Antibody |
| Also known as: |
p21 (AF9D10) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
p21 |
| Specificity: |
This is a highly specific antibody against p21 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
AF9D10 |
| Concentration: |
1ug per 1ul |
| Source: |
Recombinant human protein purified from E, coli (His-ABD-p21) |
| Gene ID number: |
1026 |
| Swiss Prot: |
P38936 |
| Tested Applications: |
WB |
| Recommended dilutions: |
5 ug/ml), WB (0 |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
At higher stoichiometric ratios, Binds to and inhibits cyclin-dependent kinase activity, Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1, inhibits the kinase activity of the cyclin D-CDK4 complex, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression, May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CAP20, CDK-interacting protein 1, CDKN1, CDKN1A, CIP1, Cyclin-dependent kinase inhibitor 1, MDA-6, MDA6, Melanoma differentiation-associated protein 6, PIC1, SDI1, WAF1, p21CIP1, P21 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
p21 (AF9D10) Monoclonal |
| Short name: |
p21 (AF9D10) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p21 (AF9D10) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |