| Also known as: |
ACTN4 |
| Other names: |
Alpha-actinin-4, F-actin cross-linking protein, F-actin cross-linking protein, Non-muscle alpha-actinin 4, actinin, actinin alpha4 isoform, alpha 4, alpha-actinin-4, focal segmental glomerulosclerosis 1, non-muscle alpha-actinin 4, alpha-actinin-4 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ACTN4 |
| Other gene names: |
ACTININ-4, ACTN4, FSGS, FSGS1, N/A, ACTN4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
4D10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human ACTN4 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 4D10] (IgG2a, k) ACTN4 |
| Short name: |
Mouse Monoclonal [clone 4D10] (IgG2a, k) ACTN4 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
a 4 (Antibody to), sapiens actinin, Mouse monoclonal [clonality 4D10] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ACTININ-4 and FSGS and FSGS1, ACTN4 and IDBG-49384 and ENSG00000130402 and 81, ACTN4 and IDBG-637203 and ENSBTAG00000011215 and 522269, Actn4 and IDBG-165033 and ENSMUSG00000054808 and 60595, actin filament binding, alpha 4, nuclei, this GO :0001666 and response to hypoxia and biological process this GO :0001725 and stress fiber and cellular component this GO :0001882 and nucleoside binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0003779 and actin binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007596 and blood coagulation and biological process this GO :0015031 and protein transport and biological process this GO :0030018 and Z disc and cellular component this GO :0030168 and platelet activation and biological process this GO :0030529 and ribonucleoprotein complex and cellular component this GO :0030863 and cortical cytoskeleton and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031143 and pseudopodium and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032417 and positive regulation of sodium:proton antiporter activity and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043005 and neuron projection and cellular component this GO :0043234 and protein complex and cellular component this GO :0044822 and poly(A) RNA binding and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048549 and positive regulation of pinocytosis and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051017 and actin filament bundle assembly and biological process this GO :0051271 and negative regulation of cellular component movement and biological process this GO :0051272 and positive regulation of cellular component movement and biological process this GO :0051764 and actin crosslink formation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :1902396 and protein localization to tight junction and biological process, this GO :0001882 : nucleoside binding, this GO :0001882 : nucleoside binding and also this GO :0003779 : actin binding and also this GO :0005178 : integrin binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding and also this GO :0042803 : protein homodimerization activity and also this GO :0044822 : poly(A) RNA binding and also this GO :0047485 : protein N-terminus binding and also this GO :0051015 : actin filament binding, this GO :0003779 : actin binding, this GO :0005178 : integrin binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, this GO :0042803 : protein homodimerization activity, this GO :0044822 : poly(A) RNA binding, this GO :0047485 : protein N-terminus binding, this GO :0051015 : actin filament binding, actinin |
| Identity: |
166 |
| Gene: |
ACTN4 |
More about : ACTN4 |
| Long gene name: |
actinin alpha 4 |
| Synonyms gene: |
FSGS1 |
| Synonyms gene name: |
focal segmental glomerulosclerosis 1 |
| Locus: |
19q13, 2 |
| Discovery year: |
1992-03-26 |
| GenBank acession: |
D89980 |
| Entrez gene record: |
81 |
| Pubmed identfication: |
9461087 10700177 |
| Classification: |
Actinins |
| Havana BLAST/BLAT: |
OTTHUMG00000137382 |