| Also known as: |
BIK |
| Other names: |
Apoptosis inducer NBK, BCL2-interacting killer (apoptosis-inducing), BIP1, BP4, Bcl-2-interacting killer, apoptosis inducer NBK, apoptosis-inducing NBK, bcl-2-interacting killer, bcl-2-interacting killer |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
BIK |
| Other gene names: |
BIK, BIP1, BP4, NBK, NBK, BIK |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
4G12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human Bik |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided, For extended periods of time, storage at -80 degrees Celsius is recommended, After aliquoting the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 4G12] BIK |
| Short name: |
Mouse Monoclonal [clone 4G12] (IgG) BIK Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens BCL2-interacting killer (apoptosis-inducing) (Antibody to), Mouse monoclonal [clonality 4G12] (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BH domain binding, BIK and IDBG-10395 and ENSG00000100290 and 638, BIP1 and BP4 and NBK, Bik and IDBG-168304 and ENSMUSG00000016758 and 12124, Plasma membranes, this GO :0005515 and protein binding and molecular function this GO :0005740 and mitochondrial envelope and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008584 and male this GO nad development and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031966 and mitochondrial membrane and cellular component this GO :0032464 and positive regulation of protein homooli this GO merization and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051400 and BH domain binding and molecular function this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0051400 : BH domain binding, this GO :0046982 : protein heterodimerization activity, this GO :0051400 : BH domain binding, BCL2-interacting killer (apoptosis-inducing) |
| Identity: |
1051 |
| Gene: |
BIK |
More about : BIK |
| Long gene name: |
BCL2 interacting killer |
| Synonyms gene name: |
BCL2-interacting killer (apoptosis-inducing) |
| Synonyms: |
NBK |
| Synonyms name: |
natural born killer |
| Locus: |
22q13, 2 |
| Discovery year: |
1996-10-26 |
| GenBank acession: |
U34584 |
| Entrez gene record: |
638 |
| Pubmed identfication: |
7478623 10591208 |
| RefSeq identity: |
NM_001197 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000150703 |