| Also known as: |
CEACAM5 / CD66e |
| Other names: |
CD_antigen: CD66e, CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100, carcinoembryonic antigen-related cell adhesion molecule 5, carcinoembryonic antigen-related cell adhesion molecule 5, meconium antigen 100, carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CEACAM5 |
| Other gene names: |
CD66e, CEA, CEA, CEA, CEACAM5, CEACAM5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
CB30 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD66e is a member of the immunoglobulin supergene family that is mainly expressed on epithelial cells, CD66e may play a role in cancer cells metastasis, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, also known as carcinoembryonic antigen (CEA), and has been used clinically as a tumor marker for early detection of disease, Recognizes human CD66e |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, 09% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), IHC - Frozen), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ CB30] (IgG1) CEACAM5 / CD66e |
| Short name: |
Mouse Monoclonal [clone CB30] (IgG1) CEACAM5 / CD66e Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens carcinoembryonic antigen-related cellular adhesion molecule 5 / CD66e (Antibody to), Mouse monoclonal [clonality CB30] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD66e and CEA, CEACAM5 and IDBG-53174 and ENSG00000105388 and 1048, Plasma membranes, protein homodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0010832 and negative regulation of myotube differentiation and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0031225 and anchored component of membrane and cellular component this GO :0034109 and homotypic cell-cell adhesion and biological process this GO :0034235 and GPI anchor binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071575 and integral component of external side of plasma membrane and cellular component this GO :2000811 and negative regulation of anoikis and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0034235 : GPI anchor binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity, this GO :0034235 : GPI anchor binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, carcinoembryonic antigen-related cell adhesion molecule 5 |
| Identity: |
1817 |
| Gene: |
CEACAM5 |
More about : CEACAM5 |
| Long gene name: |
carcinoembryonic antigen related cell adhesion molecule 5 |
| Synonyms gene: |
CEA |
| Synonyms gene name: |
carcinoembryonic antigen-related cell adhesion molecule 5 |
| Synonyms: |
CD66e |
| Locus: |
19q13, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M17303 |
| Entrez gene record: |
1048 |
| RefSeq identity: |
NM_004363 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing CD molecules V-set domain containing Carcinoembryonic antigen related cell adhesion molecule family |
| Havana BLAST/BLAT: |
OTTHUMG00000151061 |