| Also known as: |
RELA / NFKB p65 |
| Other names: |
NF-kappa-B p65delta3, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Transcription factor p65, nuclear factor NF-kappa-B p65 subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog A, v-rel reticuloendotheliosis viral oncogene homolog A, transcription factor p65 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
RELA |
| Gene name synonims: |
NFKB |
| Other gene names: |
NFKB3, NFKB3, RELA, p65, RELA |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
112A1021 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Bovine, Chimpanzee, Dog, Due to limited knowledge and inability for testing each and every species, Gorilla, Horse (at least 90% immunogen sequence identity), Human (Homo sapiens), Monkey, Mouse (Mus musculus), Orangutan, Pig <, the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Bat, Gibbon, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
It will cross-react with mouse NF-kB p65, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, A synthetic peptide corresponding to amino acids 526-539 of human NF-kB (p65) protein |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
Sourced in TCS, 05% BSA and 0, 05% sodium azide, PBS containing 0 |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 112A1021] (IgG1, k) RELA / NFKB p65 |
| Short name: |
Mouse Monoclonal [clone 112A1021] (IgG1, k) RELA / NFKB p65 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens v-v-rel reticuloendotheliosis viral oncogene homolog (avian) reticuloendotheliosis viral oncogene homolog A (avian) / NFKB p65 (Antibody to), Mouse monoclonal [clonality 112A1021] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007568 and aging and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009617 and response to bacterium and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010033 and response to organic substance and biological process this GO :0010035 and response to inorganic substance and biological process this GO :0010224 and response to UV-B and biological process this GO :0014040 and positive regulation of Schwann cell differentiation and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016032 and viral process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032570 and response to progesterone and biological process this GO :0032868 and response to insulin and biological process this GO :0033590 and response to cobalamin and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0034097 and response to cytokine and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042301 and phosphate ion binding and molecular function this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043200 and response to amino acid and biological process this GO :0043234 and protein complex and cellular component this GO :0043278 and response to morphine and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045084 and positive regulation of interleukin-12 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051591 and response to cAMP and biological process this GO :0051607 and defense response to virus and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0070555 and response to interleukin-1 and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071316 and cellular response to nicotine and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071354 and cellular response to interleukin-6 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071375 and cellular response to peptide hormone stimulus and biological process this GO :0071532 and ankyrin repeat binding and molecular function this GO :2000630 and positive regulation of miRNA metabolic process and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, NFKB3 and p65, RELA and IDBG-57543 and ENSG00000173039 and 5970, Rela and IDBG-132298 and ENSMUSG00000024927 and 19697, ankyrin repeat binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001205 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001889 and liver development and biological process this GO :0001942 and hair follicle development and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006117 and acetaldehyde metabolic process and biological process this GO :0006355 and regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0032403 : protein complex binding and also this GO :0033613 : activating transcription factor binding and also this GO :0042301 : phosphate ion binding and also this GO :0042802 : identical protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0047485 : protein N-terminus binding and also this GO :0051059 : NF-kappaB binding and also this GO :0070491 : repressing transcription factor binding and also this GO :0071532 : ankyrin repeat binding, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0032403 : protein complex binding, this GO :0033613 : activating transcription factor binding, this GO :0042301 : phosphate ion binding, this GO :0042802 : identical protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0047485 : protein N-terminus binding, this GO :0051059 : NF-kappaB binding, this GO :0070491 : repressing transcription factor binding, this GO :0071532 : ankyrin repeat binding, 26220 and IDBG-644222 and ENSBTAG00000013895 and 508233, v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
| Identity: |
9955 |
| Gene: |
RELA |
More about : RELA |
| Long gene name: |
NF-kB subunit , RELA proto-oncogene |
| Synonyms gene: |
NFKB3 |
| Synonyms gene name: |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 v-rel avian reticuloendotheliosis viral oncogene homolog A |
| Synonyms: |
p65 |
| Locus: |
11q13, 1 |
| Discovery year: |
1991-11-14 |
| GenBank acession: |
Z22951 |
| Entrez gene record: |
5970 |
| Pubmed identfication: |
2001591 |
| RefSeq identity: |
NM_021975 |
| Classification: |
NF-kappa B complex subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000166566 |