| Also known as: |
MAdCAM-1 |
| Other names: |
MAdCAM-1, Mucosal addressin cell adhesion molecule 1, N/A, hMAdCAM-1, mucosal addressin cell adhesion molecule 1, mucosal addressin cell adhesion molecule-1, mucosal vascular addressin cell adhesion molecule 1, mucosal addressin cell adhesion molecule 1 isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MADCAM1 |
| Gene name synonims: |
MAdCAM-1 |
| Other gene names: |
MACAM1, MADCAM1, MAdCAM-1, hMAdCAM-1, MADCAM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
314G8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7, Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8, MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues, MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 60kD cell surface protein that is involved in lymphocyte trafficking, Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Store undiluted, We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 314G8] (IgG1) MAdCAM-1 |
| Short name: |
Mouse Monoclonal [clone 314G8] (IgG1) MAdCAM-1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens MAdCAM-1 (Antibody to), Mouse monoclonal [clonality 314G8] (IgG1) to H |
| Alternative technique: |
antibodies |