| Also known as: |
SNAP25 |
| Other names: |
25kD, 25kDa, SUP, SUP, Super protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, resistance to inhibitors of cholinesterase 4 homolog, super protein, synaptosomal-associated protein, synaptosomal-associated protein, synaptosomal-associated protein 25, synaptosomal-associated protein 25 isoform SNAP25A |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SNAP25 |
| Other gene names: |
RIC-4, RIC4, SEC9, SNAP, SNAP, SNAP-25, SNAP-25, SNAP25, SUP, bA416N4, dJ1068F16, 2, 2, SNAP25 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
SP12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Pig, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Hamster |
| Specificity and cross-reactivity: |
It will recognize SNAP-25 fusion protein from COS cells, Research studies have used this antibody to study the distribution of synaptic changes in the hippocampus of patients with medically refractory temporal lobe epilepsy, SNAP-25, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, an antigen of 26-27kD molecular weight, but not with the fusion protein from bacterial systems, Appears to recognize the human pre-synaptic protein |
| Purification method: |
Tissue culture supernatant |
| Form/Appearance: |
0, Sourced in TCS, pH 7, 09% sodium azide, 2, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ SP12] (IgG1) SNAP25 |
| Short name: |
Mouse Monoclonal [clone SP12] (IgG1) SNAP25 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
25kDa (Antibody to), sapiens synaptosomal-associated protein, Mouse monoclonal [clonality SP12] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
25kDa, Cell surfaces, SNAP25 and IDBG-53941 and ENSG00000132639 and 6616, SNAP25 and IDBG-636453 and ENSBTAG00000008323 and 540853, Snap25 and IDBG-207842 and ENSMUSG00000027273 and 20614, bA416N4, protein binding, this GO :0000149 and SNARE binding and molecular function this GO :0001504 and neurotransmitter uptake and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0010975 and regulation of neuron projection development and biological process this GO :0014047 and glutamate secretion and biological process this GO :0016020 and membrane and cellular component this GO :0016081 and synaptic vesicle docking involved in exocytosis and biological process this GO :0016192 and vesicle-mediated transport and biological process this GO :0030054 and cell junction and cellular component this GO :0030426 and growth cone and cellular component this GO :0031083 and BLOC-1 complex and cellular component this GO :0031201 and SNARE complex and cellular component this GO :0043005 and neuron projection and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0045202 and synapse and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050796 and regulation of insulin secretion and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0070032 and synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex and cellular component this GO :0070201 and regulation of establishment of protein localization and biological process, this GO :0000149 : SNARE binding, this GO :0000149 : SNARE binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 2 and RIC-4 and RIC4 and SEC9 and SNAP and SNAP-25, 2 and dJ1068F16, synaptosomal-associated protein |
| Identity: |
11132 |
| Gene: |
SNAP25 |
More about : SNAP25 |
| Long gene name: |
synaptosome associated protein 25 |
| Synonyms gene: |
SNAP |
| Synonyms gene name: |
25kDa , synaptosomal-associated protein |
| Synonyms: |
SNAP-25 RIC-4 RIC4 SEC9 bA416N4, 2 , 2 dJ1068F16 |
| Synonyms name: |
resistance to inhibitors of cholinesterase 4 homolog |
| Locus: |
20p12, 2 |
| Discovery year: |
1995-01-24 |
| Entrez gene record: |
6616 |
| Pubmed identfication: |
8661740 10692432 |
| RefSeq identity: |
NM_130811 |
| Classification: |
SNAREs |
| Havana BLAST/BLAT: |
OTTHUMG00000031863 |