| Also known as: |
TP73 / p73 |
| Other names: |
Tumor protein p73, p53-like transcription factor, p53-like transcription factor, p53-related protein, p53-related protein, tumor protein p73, tumor protein p73, tumor protein p73 isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TP73 |
| Gene name synonims: |
p73 |
| Other gene names: |
P73, P73, TP73, TP73 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
5B429 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
It does not cross react with p53, It reacts with an epitope that is located on the N-terminal region of human p73, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Full-length human p73 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
05% BSA and 0, 05% sodium azide, PBS containing 0 |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 5B429] TP73 / p73 |
| Short name: |
Mouse Monoclonal [clone 5B429] (IgG) TP73 / p73 Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens tumor protein p73 / p73 (Antibody to), Mouse monoclonal [clonality 5B429] (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006954 and inflammatory response and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006978 and DNA damage response, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048546 and digestive tract morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0051262 and protein tetramerization and biological process this GO :1902167 and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, P73, TP73 and IDBG-634515 and ENSBTAG00000005812 and 515105, TP73 and IDBG-86757 and ENSG00000078900 and 7161, Trp73 and IDBG-206900 and ENSMUSG00000029026 and 22062, metal ion binding, nuclei, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010165 and response to X-ray and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0021766 and hippocampus development and biological process this GO :0030900 and forebrain development and biological process this GO :0031571 and mitotic G1 DNA damage checkpoint and biological process this GO :0033326 and cerebrospinal fluid secretion and biological process this GO :0034644 and cellular response to UV and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045793 and positive regulation of cell size and biological process this GO :0045893 and positive regulation of transcription, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0000785 and chromatin and cellular component this GO :0001822 and kidney development and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0002039 and p53 binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005829 and cytosol and cellular component this GO :0006298 and mismatch repair and biological process this GO :0006351 and transcription, this GO :0002039 : p53 binding, this GO :0002039 : p53 binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003684 : damaged DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019901 : protein kinase binding and also this GO :0042802 : identical protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003684 : damaged DNA binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019901 : protein kinase binding, this GO :0042802 : identical protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, tumor protein p73 |
| Identity: |
12003 |
| Gene: |
TP73 |
More about : TP73 |
| Long gene name: |
tumor protein p73 |
| Synonyms: |
P73 |
| Locus: |
1p36, 32 |
| Discovery year: |
1997-11-12 |
| GenBank acession: |
AB055065 |
| Entrez gene record: |
7161 |
| Pubmed identfication: |
9296498 9288759 |
| RefSeq identity: |
NM_005427 |
| Havana BLAST/BLAT: |
OTTHUMG00000000610 |