| Also known as: |
CD68 |
| Other names: |
CD68 antigen, CD68 molecule, Gp110, Macrosialin, macrophage antigen CD68, macrosialin, member 1, scavenger receptor class D, macrosialin isoform B |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD68 |
| Other gene names: |
CD68, GP110, LAMP4, N/A, SCARD1, CD68 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
Ki-M7 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD68 can be used to aid in the identification of blastic NK lymphomas, Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D_Clone Ki-M7 has also been reported as being suitable for use in immunoprecipitation studies, _x000D__x000D_In immunohistochemical studies, and is expressed to a lesser extent by dendritic cells and peripheral blood granulocytes, and to help diagnose disorders relating to macrophage abnormalities, histiocytes and osteoclasts, including Acute Myeloid Leukemia, including Kupffer cells, including malignant histocytosis and Gaucher's disease, microglia, some B cell lymphomas, CD68 This item recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of macrophages/monocytes, _x000D__x000D_ |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
2 mg/ml after reconstitution, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 12 months from date of reconstitution, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology - Frozen (IHC), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD68 |
| Short name: |
MOUSE Anti-HUMAN CD68 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD68 molecule (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD68 and IDBG-25923 and ENSG00000129226 and 968, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, GP110 and LAMP4 and SCARD1, Plasma membranes, this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0071310 and cellular response to organic substance and biological process, CD68 molecule |
| Identity: |
1693 |
| Gene: |
CD68 |
More about : CD68 |
| Long gene name: |
CD68 molecule |
| Synonyms gene name: |
CD68 antigen |
| Synonyms: |
SCARD1 macrosialin GP110 DKFZp686M18236 LAMP4 |
| Synonyms name: |
member 1 CD68 antigen macrophage antigen CD68 , scavenger receptor class D |
| Locus: |
17p13, 1 |
| Discovery year: |
1993-06-11 |
| GenBank acession: |
S57235 |
| Entrez gene record: |
968 |
| Pubmed identfication: |
9790779 |
| RefSeq identity: |
NM_001251 |
| Classification: |
CD molecules Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000108146 |