| Also known as: |
CD3 |
| Other names: |
CD3 antigen, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, epsilon polypeptide, T-cell surface glycoprotein CD3 epsilon chain |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD3 |
| Other gene names: |
AI504783, CD3, CD3epsilon, Cd3e, N/A, T3e, Cd3e |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
145-2C11 |
| Host organism: |
Hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD3e is a member of the CD3 complex which consists of four subunits, It interacts non-covalently with the CD3 dimers delta/epsilon, NK-T cells and at different levels on thymocytes during T cell differentiation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, T cell depletions, TCR plays a critical role in T cell development and function and is responsible for ligand recognition, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD3e is primarily expressed on T cells, _x000D__x000D_The 145-2C11 antibody is useful for <, a 20kDa transmembrane protein also known as CD3 or T3, as well as apoptosis induction and <, blocking and activation assays, delta, epsilon and zeta and these are associated to the T cell receptor (TCR), gamma, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell, /i>, /i>, CD3 This item detects CD3 epsilon (CD3e), i>, i>, in vitro<, in vitro< |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD3 |
| Short name: |
HAMSTER ANTI MOUSE CD3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HAMSTER antibody to MOUSE CD3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24219 |
| Gene: |
CD3EAP |
More about : CD3EAP |
| Long gene name: |
CD3e molecule associated protein |
| Synonyms gene name: |
CD3e antigen, epsilon associated protein , epsilon polypeptide associated protein CD3e molecule |
| Synonyms: |
ASE-1 CAST PAF49 |
| Synonyms name: |
CD3 epsilon associated protein antisense to ERCC 1 |
| Locus: |
19q13, 32 |
| Discovery year: |
2005-04-21 |
| GenBank acession: |
U86751 |
| Entrez gene record: |
10849 |
| Pubmed identfication: |
10373416 9426281 15226435 |
| RefSeq identity: |
NM_012099 |
| Havana BLAST/BLAT: |
OTTHUMG00000182120 |