| Also known as: |
CD18 |
| Other names: |
Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, Mac-1 beta, cell surface adhesion glycoproteins LFA-1/CR3/p150, complement receptor C3 subunit beta, integrin beta 2, integrin beta-2, lymphocyte function associated antigen 1, macrophage antigen-1 beta, 95 subunit beta, 95 subunit beta, integrin beta-2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD18 |
| Other gene names: |
2E6, AI528527, Cd18, Itgb2, LAD, LCAMB, Lfa1, MF17, N/A, Itgb2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
M18/2 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD11b/CD18 and CD11c/CD18 respectively, CD18 is a 95KD cell surface glycoprotein that forms heterodimers with the integrin subunit alpha L (CD11a), CD18 is expressed by all leucocytes and plays an important role in adhesion and signalling in the haematopoietic system, Clone M18/2 has been reported to both inhibit and enhance certain functions of CD18 (please refer to references 2 and 3), Removal of sodium azide is recommended prior to use in functional assays -, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, alpha M (CD11b) or alpha X (CD11c) to produce integrins CD11a/CD18, CD18 Recognises the murine beta 2 integrin (CD18) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Western Blot (WB), Immunoprecipitation (IP) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD18 |
| Short name: |
RAT ANTI MOUSE CD18 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD18 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6155 |
| Gene: |
ITGB2 |
More about : ITGB2 |
| Long gene name: |
integrin subunit beta 2 |
| Synonyms gene: |
CD18 MFI7 |
| Synonyms gene name: |
beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin |
| Synonyms: |
LFA-1 MAC-1 |
| Synonyms name: |
complement component 3 receptor 3 and 4 subunit |
| Locus: |
21q22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK222505 |
| Entrez gene record: |
3689 |
| RefSeq identity: |
NM_000211 |
| Classification: |
Complement system Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000090257 |
| Locus Specific Databases: |
ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76 |