| Also known as: |
PAPILLOMAVIRUS 18 ONCOPROTEIN E7 |
| Other names: |
N/A, N/A, N/A, Protein E7, Protein E7 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
E7, N/A, N/A, N/A |
| Gene name synonims: |
E7, N/A, N/A, N/A |
| Other gene names: |
E7, N/A, N/A, N/A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
718-15 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Viral |
| Specificity and cross-reactivity: |
E7 particularly binds to Rb and histone deacetylases, Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Some HPV types are the causative agents of cervical cancer, The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_This item does not cross-react with the E7 protein of HPV-16, also a tumor-supressor), resulting in activation of the E2F genes, since they are expressed early in viral infection, which code for a family of transcription factors, with types 16 and 18 being particularly high-risk, PAPILLOMAVIRUS 18 ONCOPROTEIN E7 This item recognises the E7 oncoprotein of human papilloma virus 18 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
PAPILLOMAVIRUS 18 ONCOPROTEIN E7 |
| Short name: |
MOUSE Anti-HUMAN PAPILLOMAVIRUS 18 ONCOPROTEIN E7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens PAPILLOMAVIRUS 18 ONCOPROTEIN E7 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |