| Also known as: |
ANTHRAX |
| Other names: |
Anthrax lethal toxin endopeptidase component, Lethal factor, N/A, pXO1-107, pXO1-107 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LF, N/A, lef, pxo1_107 |
| Gene name synonims: |
LF, N/A, lef, pxo1_107 |
| Other gene names: |
LF, N/A, lef, pxo1_107 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
LFA58 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Bacterial |
| Specificity and cross-reactivity: |
<, Both EF and LF functions intracellularly but are too large to enter the cell through existing channels, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The LF acts as an endoprotease, The PA is responsible for transporting the EF and LF into cells, The kinases are prevented from binding to their substrates, The three proteins depend on each other for their toxic effect, This particular antibody might cross react with speacies outside of the listed ones, produces a toxin composed of three proteins, removing the N-terminus of mitogen-activated protein kinase kinases (MAPKK), the Edema Factor (EF) and the Lethal Factor (LF), the Protective Antigen (PA), which leads to altered signalling pathways and ultimately to apoptosis, /i>, ANTHRAX This item recognises the Lethal Factor of the anthrax toxin, Bacillus anthracis<, i> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ANTHRAX LETHAL FACTOR |
| Short name: |
MOUSE Anti-ANTHRAX LETHAL FACTOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-ANTHRAX LETHAL FACTOR (Antibody to) |
| Alternative technique: |
antibodies |