| Also known as: |
ANNEXIN V |
| Other names: |
Anchorin CII, Annexin A5, Annexin V, Annexin-5, CBP-I, CBP-I, Calphobindin I, Endonexin II, Lipocortin V, PAP-I, PAP-I, PP4, Placental anticoagulant protein 4, Placental anticoagulant protein I, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha, anchorin CII, annexin A5, annexin A5, annexin V, annexin-5, calphobindin I, endonexin II, lipocortin V, placental anticoagulant protein 4, placental anticoagulant protein I, thromboplastin inhibitor, vascular anticoagulant-alpha, annexin A5 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ANX5, ANX5, ANXA5, CBP-I, ENX2, ENX2, PAP-I, PP4, PP4, PP4, RPRGL3, VAC-alpha, ANXA5 |
| Gene name synonims: |
ANX5, ANX5, ANXA5, CBP-I, ENX2, ENX2, PAP-I, PP4, PP4, PP4, RPRGL3, VAC-alpha, ANXA5 |
| Other gene names: |
ANX5, ANX5, ANXA5, CBP-I, ENX2, ENX2, PAP-I, PP4, PP4, PP4, RPRGL3, VAC-alpha, ANXA5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
VAA-33 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The presence of antibodies to Annexin V, The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), acts as an in vivo signal for the removal of the dying cell by phagocytosis, are associated with systemic lupus erythematosus (SLE), by acting as an inhibitor of prothrombin activation, due to a loss in plasma membrane asymmetry during apoptosis, in the presence of calcium, recurrent spontaneous abortions and systemic sclerosis (SSc), ANNEXIN V This item specifically recognises human Annexin V |
| Form/Appearance: |
FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration: |
2 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Anti-FITC Antibody |
| Gene target: |
ANNEXIN V: |
| Short name: |
MOUSE Anti-HUMAN ANNEXIN V:FITC Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label: |
FITC |
| Alternative name: |
sapiens ANNEXIN V:fluorecein (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |