| Also known as: |
SC5b-9 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SC5b-9 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
3R2/0 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Both the classical and alternative complement pathways result in the formation of the cytolysis inducing C5b-9 complex, Clone 3R2/0 has been reprted to work in western blotting applications, Removal of Sodium Azide is recommended prior to use in functional assays, SC5b-9 is stable in vitro and is therefore a reliable indicator of terminal complement pathway activation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Sublytic assembly of C5b-9 on plasma membranes induces cell cycle activation and survival, The binding of C5b-9 to the 75 kDa S-protein (or vitronectin) in the fluid phase prevents C5b-9 from assembling on the plasma membrane, This complex is composed of 190 kDa C5b which is bound to cells via 71 kDa C9, This particular antibody might cross react with speacies outside of the listed ones, deactivating it and forming the SC5b-9 complex, SC5b-9 This item recognises the SC5b-9 complex of around 330 kDa |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
SC5b-9 |
| Short name: |
MOUSE Anti-HUMAN SC5b-9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens SC5b-9 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |