| known also as: |
Anti-GOAT ANTI Bcl-2 (N-TERMINAL) |
| known also as: |
Caprine ANTI Bcl-2 (N-TERMINAL) |
| known also as: |
Caprinae ANTI Bcl-2 (N-TERMINAL) |
| known also as: |
Bcl-2 |
| Other names: |
Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, N/A, apoptosis regulator Bcl-2, protein phosphatase 1, regulatory subunit 50, apoptosis regulator Bcl-2 alpha isoform |
| Gene name: |
Bcl-2 |
| Other gene names: |
BCL2, Bcl-2, N/A, PPP1R50, BCL2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Bcl-2 is antiproliferative by facilitating G<, Bcl-2 mutations have also been found in Non-Hodgkin Lymphomas, Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability, It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (apaf-1), a 25kD integral outer mitochondrial membrane protein that blocks apoptotic death in a variety of cell systems, also known as type II chronic lymphatic leukaemia, entry, /sub>, 0<, Bcl-2 This item detects an epitope within the N-terminal (NT) region of Bcl-2, _x000D__x000D_Constitutive expression of Bcl-2 is thought to be the cause of follicular lymphoma, sub> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
Bcl-2 |
| Short name: |
GOAT ANTI Bcl-2 (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
caprine antibody to Bcl-2 (N-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
990 |
| Gene: |
BCL2 |
More about : BCL2 |
| Long gene name: |
BCL2, apoptosis regulator |
| Synonyms gene name: |
B-cell CLL/lymphoma 2 |
| Synonyms: |
Bcl-2 PPP1R50 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 50 |
| Locus: |
18q21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M14745 |
| Entrez gene record: |
596 |
| RefSeq identity: |
NM_000633 NM_000657 |
| Classification: |
Protein phosphatase 1 regulatory subunits BCL2 family |
| Havana BLAST/BLAT: |
OTTHUMG00000132791 |
| Locus Specific Databases: |
LRG_1113 |