| known also as: |
Anti-GOAT ANTI HUMAN NOXA |
| known also as: |
Caprine ANTI HUMAN NOXA |
| known also as: |
Caprinae ANTI Homo sapiens NOXA |
| known also as: |
NOXA |
| Other names: |
Immediate-early-response protein APR, PMA-induced protein 1, Phorbol-12-myristate-13-acetate-induced protein 1, Protein Noxa, adult T cell leukemia-derived PMA-responsive, immediate-early-response protein APR, phorbol-12-myristate-13-acetate-induced protein 1, phorbol-12-myristate-13-acetate-induced protein 1, protein Noxa, phorbol-12-myristate-13-acetate-induced protein 1 |
| Gene name: |
NOXA |
| Other gene names: |
APR, NOXA, NOXA, PMA-induced protein 1, PMAIP1, PMAIP1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
IFNbeta, _x000D__x000D_Noxa is a transcriptional target of p53, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, and BIM, and acts as promoter of caspase and apoptosis activation, and competes with, and displaces, dsRNA and viruses, from the antiapoptotioc protein MCL1 (Bcl-2-related protein EAT/mcl1), p73 and BH3-only proteins, phorbol esters, the proapoptotic proteins BAK1, thereby influencing apoptosis versus cell survival, which is up-regulated by p53, NOXA This item specifically recognises human Noxa |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
NOXA |
| Short name: |
GOAT ANTI HUMAN NOXA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens NOXA (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
9108 |
| Gene: |
PMAIP1 |
More about : PMAIP1 |
| Long gene name: |
phorbol-12-myristate-13-acetate-induced protein 1 |
| Synonyms: |
APR NOXA |
| Locus: |
18q21, 32 |
| Discovery year: |
1991-08-12 |
| GenBank acession: |
D90070 |
| Entrez gene record: |
5366 |
| Pubmed identfication: |
2398525 12879012 |
| RefSeq identity: |
NM_021127 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000132765 |