| known also as: |
Anti-RABBIT ANTI MOUSE DACT1 |
| known also as: |
RABBIT ANTI Murine DACT1 |
| known also as: |
Lapin ANTI Mus musculus DACT1 |
| known also as: |
DACT1 |
| Other names: |
Dapper antagonist of catenin 1, Dapper homolog 1, Frodo homolog, MDpr1, Thymus-expressed novel gene 3 protein, antagonist of beta-catenin (xenopus), dapper 1, dapper antagonist of catenin 1, dapper homolog 1, dapper homolog 1, frodo homolog, thymus expressed gene 3, thymus-expressed novel gene 3 protein, dapper homolog 1 isoform 2 |
| Gene name: |
DACT1 |
| Other gene names: |
4921528D17Rik, AI115603, DAPPER, DAPPER1, Dact1, FRODO, Frd1, Frodo1, MDpr1, MTNG3, THYEX3, Thyex3, Dact1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse |
| Specificity and cross-reactivity: |
Dact1 is involved in enhancement of the transcriptional activation of target genes of the Wnt signalling pathway, Studies have shown that mice homozygous for mutations in Dact1, a cytoplasmic protein which plays a pivotal role in Wnt signalling during vertebrate development, an intracellular protein and member of the dapper family, display malformations involving the spine, genitourinary system and distal digestive tract, through its intracellular co-localization with DVL2 and inhibition of the degradation of CTNNB1/beta-catenin, which acts as a positive regulator of the signalling pathways of Dishevelled 2 (DVL2), which was traced to disrupted germ-layer morphogenesis at the primitive streak, DACT1 This item recognises mouse Dact1 (Dapper homolog 1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
DACT1 |
| Short name: |
Anti-MOUSE DACT1 |
| Alternative name: |
antibody to-MOUSE DACT1 |
| Identity: |
17748 |
| Gene: |
DACT1 |
More about : DACT1 |
| Long gene name: |
dishevelled binding antagonist of beta catenin 1 |
| Synonyms gene name: |
antagonist of beta-catenin, antagonist of beta-catenin (xenopus) dapper, dapper homolog 1, homolog 1 (Xenopus laevis) |
| Synonyms: |
DAPPER1 THYEX3 HDPR1 DAPPER FRODO |
| Locus: |
14q23, 1 |
| Discovery year: |
2003-01-15 |
| GenBank acession: |
AF251079 |
| Entrez gene record: |
51339 |
| Pubmed identfication: |
11970895 |
| RefSeq identity: |
NM_016651 |
| Havana BLAST/BLAT: |
OTTHUMG00000140324 |