| Also known as: |
CD180 |
| Other names: |
CD180 antigen, CD180 antigen, CD180 antigen, Ly-78, Lymphocyte antigen 78, Radioprotective 105 kDa protein, ly-78, lymphocyte antigen 78, radioprotective 105 kDa protein, CD180 antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD180 |
| Other gene names: |
Cd180, F630107B15, Ly-78, Ly78, Ly78, RP105, Rp105, Cd180 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
RP/14 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
B-cell proliferation and up-regulation of a co-stimulatory molecule B7, CD180 is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, through co-operation with MD-1 and TLR4, which belongs to the toll-like receptor family, 2 Removal of sodium azide is recommended prior to use in functional studies, CD180 Clone RP/14 recognizes mouse CD180 (RP105) a 105kD type 1 transmembrane protein |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Functional Assay (FA), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD180 |
| Short name: |
RAT ANTI MOUSE CD180 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD180 molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD180 and IDBG-24968 and ENSG00000134061 and 4064, Cd180 and IDBG-179053 and ENSMUSG00000021624 and 17079, LY64 and Ly78 and RP105, Plasma membranes, protein binding, this GO :0002322 and B cell proliferation involved in immune response and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0031666 and positive regulation of lipopolysaccharide-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 22214 and IDBG-628694 and ENSBTAG00000006360 and 539518, CD180 molecule |
| Identity: |
6726 |
| Gene: |
CD180 |
More about : CD180 |
| Long gene name: |
CD180 molecule |
| Synonyms gene: |
LY64 |
| Synonyms gene name: |
105kD CD180 antigen , lymphocyte antigen 64 (mouse) homolog, radioprotective |
| Synonyms: |
RP105 Ly78 |
| Locus: |
5q12, 3 |
| Discovery year: |
1996-05-07 |
| GenBank acession: |
D83597 |
| Entrez gene record: |
4064 |
| Pubmed identfication: |
9763566 8975706 |
| RefSeq identity: |
NM_005582 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000131229 |