| known also as: |
Anti-GOAT ANTI HUMAN TAGLN (C-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN TAGLN (C-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens TAGLN (C-TERMINAL) |
| known also as: |
TAGLN |
| Other names: |
22 kDa actin-binding protein, 22 kDa actin-binding protein, Protein WS3-10, SM22-alpha, Smooth muscle protein 22-alpha, Transgelin, smooth muscle protein 22-alpha, transgelin, transgelin, transgelin variant 2, transgelin |
| Gene name: |
TAGLN |
| Other gene names: |
SM22, SM22, SM22-alpha, SMCC, TAGLN, TAGLN1, WS3-10, WS3-10, TAGLN |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Studies have identified TAGLN as a novel tumor suppressor protein, _x000D__x000D_TAGLN is ubiquitously expressed by vascular and visceral smooth muscle, a shape change sensitive, actin cross-linking/gelling protein, and also overexpressed by senescent human fibroblasts, and an early marker of smooth muscle differentiation, and may serve as an important biomarker of malignancy, and member of the calponin family, otherwise known as SM22-alpha, which has a markedly reduced expression in colorectal cancer samples, which plays a role in calcium interactions and contractile properties of the cell, TAGLN This item specifically recognises an epitope within the C-terminal (CT) region of human TAGLN (Transgelin) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
TAGLN |
| Short name: |
GOAT ANTI HUMAN TAGLN (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens TAGLN (C-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
11553 |
| Gene: |
TAGLN |
More about : TAGLN |
| Long gene name: |
transgelin |
| Synonyms: |
SM22 WS3-10 TAGLN1 SMCC DKFZp686P11128 |
| Synonyms name: |
SM22-alpha transgelin variant 2 |
| Locus: |
11q23, 2 |
| Discovery year: |
1998-01-16 |
| GenBank acession: |
M95787 |
| Entrez gene record: |
6876 |
| Pubmed identfication: |
8117285 1520290 |
| RefSeq identity: |
NM_001001522 |
| Havana BLAST/BLAT: |
OTTHUMG00000167067 |