| known also as: |
Anti-RABBIT ANTI NAK (C-TERMINAL) |
| known also as: |
RABBIT ANTI NAK (C-TERMINAL) |
| known also as: |
Lapin ANTI NAK (C-TERMINAL) |
| known also as: |
NAK |
| Other names: |
NF-kB-activating kinase, NF-kappa-B-activating kinase, NF-kappa-B-activating kinase, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, TANK-binding kinase 1, serine/threonine-protein kinase TBK1, serine/threonine-protein kinase TBK1 |
| Gene name: |
NAK |
| Other gene names: |
NAK, NAK, T2K, TBK1, TBK1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
IKK Beta, IKK Gamma or IKK Epsilon, In addition, It also mediates the production of IFN Beta and CCL5 and plays a key role in the innate immune response, It is involved in the signalling cascade of NF-kB activation by directly phosphorylating and activating IKK Beta, It may also be involved in the induction of the antiviral interferon response, NAK is expressed ubiquitously, _x000D__x000D_This item does not cross-react with IKK Alpha, eventually leading to the development of a cellular antiviral state, it phosphorylates and activates the interferon regulatory factors -3 and -7, otherwise known as TANK-binding kinase 1 (TBK1), with higher expression in testis, NAK This item recognises human NF-kB-activating kinase (NAK) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Frozen (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
NAK |
| Short name: |
Anti-NAK (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-NAK (C-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11584 |
| Gene: |
TBK1 |
More about : TBK1 |
| Long gene name: |
TANK binding kinase 1 |
| Synonyms gene name: |
TANK-binding kinase 1 |
| Synonyms: |
NAK |
| Locus: |
12q14, 2 |
| Discovery year: |
2000-06-08 |
| GenBank acession: |
AF191838 |
| Entrez gene record: |
29110 |
| Pubmed identfication: |
10581243 10783893 |
| RefSeq identity: |
NM_013254 |
| Havana BLAST/BLAT: |
OTTHUMG00000168796 |