| known also as: |
Anti-RABBIT ANTI HUMAN LOX-1 (CYTOPLASMIC DOMAIN) |
| known also as: |
RABBIT ANTI HUMAN LOX-1 (CYTOPLASMIC DOMAIN) |
| known also as: |
Lapin ANTI Homo sapiens LOX-1 (CYTOPLASMIC DOMAIN) |
| known also as: |
LOX-1 |
| Other names: |
C-type lectin domain family 8 member A, C-type lectin domain family 8 member A, LOX-1, Lectin-like oxLDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-type oxidized LDL receptor 1, Oxidized low-density lipoprotein receptor 1, hLOX-1, hLOX-1, lectin-type oxidized LDL receptor 1, member 1, ox LDL receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, scavenger receptor class E, soluble form, oxidized low-density lipoprotein receptor 1 isoform 2 |
| Gene name: |
LOX-1 |
| Other gene names: |
CLEC8A, CLEC8A, LOX-1, LOX1, LOX1, LOXIN, Lectin-like oxLDL receptor 1, OLR1, Ox-LDL receptor 1, SCARE1, SLOX1, hLOX-1, OLR1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
It is a Type II membrane protein with a typical C-type lectin structure at the extracellular C-terminus which recognises the ligand, LOX-1 activation by oxidised LDL causes endothelial changes such as decreased nitric oxide release and an increased expression of adhesion molecules, LOX-1 also binds activated platelets and apoptotic cells, The expression of LOX-1 is induced by proatherogenic conditions such as hyperlipidemia, This receptor mediates the recognition, a receptor for oxidised low-density lipoproteins (LDL), hypertension and diabetes and as such appears to contribute to the pathogenesis of vascular disorders, internalisation and degradation of oxidised LDL, particularly atherosclerosis, LOX-1 This item recognises the cytoplasmic (N-terminal) domain of human LOX-1 |
| Form/Appearance: |
Serum (Serum - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunofluorescence (IF), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
LOX-1 (CYTOPLASMIC DOMAIN) |
| Short name: |
Anti-HUMAN LOX-1 (CYTOPLASMIC DOMAIN) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens LOX-1 (CYTOPLASMIC DOMAIN) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8133 |
| Gene: |
OLR1 |
More about : OLR1 |
| Long gene name: |
oxidized low density lipoprotein receptor 1 |
| Synonyms gene name: |
oxidised low density lipoprotein (lectin-like) receptor 1 |
| Synonyms: |
LOX-1 SCARE1 CLEC8A |
| Locus: |
12p13, 2 |
| Discovery year: |
1998-01-16 |
| GenBank acession: |
D89050 |
| Entrez gene record: |
4973 |
| Pubmed identfication: |
9763655 |
| RefSeq identity: |
NM_002543 |
| Classification: |
Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000168527 |