| Also known as: |
CD140a |
| Other names: |
Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140 antigen-like family member A, CD140a antigen, CD140a antigen, PDGF-R-alpha, PDGFR-alpha, PDGFRA/BCR fusion, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, Platelet-derived growth factor receptor alpha, alpha polypeptide, alpha-type platelet-derived growth factor receptor, platelet-derived growth factor receptor, platelet-derived growth factor receptor 2, platelet-derived growth factor receptor alpha, rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein, platelet-derived growth factor receptor alpha |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD140a |
| Other gene names: |
CD140A, PDGF-R-alpha, PDGFR-2, PDGFR-2, PDGFR-alpha, PDGFR2, PDGFR2, PDGFRA, RHEPDGFRA, RHEPDGFRA, PDGFRA |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
35248 (57/20) |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, Both PDGF receptor alpha and beta are members of the class III subfamily of receptor tyrosine kinases, PDGF R beta binds PDGF-BB and AB but not PDGF-AA, PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulphide-linked PDGF-A and PDGF-B chains, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cellsurface PDGF receptors with different affinities, Removal of Sodium Azide is recommended prior to use in functional assays, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ND50 was determined as 0, The PDGF-AA, This clone has been reported for use in functional studies, This particular antibody might cross react with speacies outside of the listed ones, Whereas PDGF receptor alpha binds all three isoforms with high affinity, 2-0, 6 ug/ml for blocking 10 ng/ml of PDGF-AA biological activity on a quiescent confluent cell culture of human WS1 cells, CD140a This item is specific for PDGF receptor alpha |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, 1 |
| Storage and shipping: |
Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD140a |
| Short name: |
MOUSE Anti-HUMAN CD140a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD140a (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8803 |
| Gene: |
PDGFRA |
More about : PDGFRA |
| Long gene name: |
platelet derived growth factor receptor alpha |
| Synonyms gene name: |
alpha polypeptide , platelet-derived growth factor receptor |
| Synonyms: |
CD140a PDGFR2 GAS9 |
| Locus: |
4q12 |
| Discovery year: |
1989-05-19 |
| GenBank acession: |
D50001 |
| Entrez gene record: |
5156 |
| Pubmed identfication: |
8643452 |
| RefSeq identity: |
NM_006206 |
| Classification: |
I-set domain containing CD molecules Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000128699 |
| Locus Specific Databases: |
LRG_309 |