| known also as: |
Anti-GOAT ANTI HUMAN TRIM5 alpha (N-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN TRIM5 alpha (N-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens TRIM5 alpha (N-TERMINAL) |
| known also as: |
TRIM5 ALPHA |
| Other names: |
RING finger protein 88, Tripartite motif-containing protein 5, ring finger protein 88, tripartite motif containing 5, tripartite motif containing 5 transcript variant iota, tripartite motif containing 5 transcript variant kappa, tripartite motif protein TRIM5, tripartite motif-containing protein 5, tripartite motif-containing protein 5 isoform alpha |
| Gene name: |
TRIM5 ALPHA |
| Other gene names: |
RNF88, RNF88, TRIM5, TRIM5alpha, TRIM5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
For example, TRIM5alpha specifically associates with HIV type 1 (HIV-1), _x000D__x000D_Studies suggest that it is the association of TRIM5 with specific retroviral capsid sequences which determines the effectiveness of the defence against infection, a cytoplasmic protein and member of the TRIM/RBCC family, but can inhibit strains of the murine leukaemia virus (MLV), in Old World monkeys, known to play a vital role in species-specific early defence against retrovirus infection, otherwise known as RNF88 (RING finger protein 88), whereas in humans TRIM5alpha is not effective against HIV-1, TRIM5 ALPHA This item specifically recognises an epitope within the N-terminal (NT) region of human TRIM5alpha |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
TRIM5 alpha |
| Short name: |
GOAT ANTI HUMAN TRIM5 alpha (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens TRIM5 a (N-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
16276 |
| Gene: |
TRIM5 |
More about : TRIM5 |
| Long gene name: |
tripartite motif containing 5 |
| Synonyms gene name: |
tripartite motif-containing 5 |
| Synonyms: |
RNF88 TRIM5alpha |
| Synonyms name: |
tripartite motif protein TRIM5 tripartite motif protein TRIM |
| Locus: |
11p15, 4 |
| Discovery year: |
2001-07-20 |
| GenBank acession: |
AF220025 |
| Entrez gene record: |
85363 |
| Pubmed identfication: |
11331580 |
| RefSeq identity: |
NM_033034 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000066893 |