| known also as: |
Anti-RABBIT ANTI MNAR |
| known also as: |
RABBIT ANTI MNAR |
| known also as: |
Lapin ANTI MNAR |
| known also as: |
MNAR |
| Other names: |
Modulator of non-genomic activity of estrogen receptor, Proline-, Transcription factor HMX3, glutamate and leucine rich protein 1, glutamic acid and leucine rich protein 1, glutamic acid-, glutamic acid- and leucine-rich protein 1, glutamic acid- and leucine-rich protein 1, glutamic acid- and leucine-rich protein 1, leucine-rich protein 1, modulator of non-genomic activity of estrogen receptor, modulator of nongenomic activity of estrogen receptor, proline, proline, proline and glutamic acid rich nuclear protein, proline-, proline-, transcription factor HMX3, proline- |
| Gene name: |
MNAR |
| Other gene names: |
HMX3, HMX3, MNAR, MNAR, P160, PELP1, PELP1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
MNAR is a src SH2-binding protein which modulates the interaction of the ER to c-Src, Other properties of MNAR include interaction with PI3K, STAT3, _x000D__x000D_MNAR acts as a transcriptional corepressor for nuclear receptors and can interact with chromatin-modifying complex components CBP (CRE-binding protein), a phosphoprotein and novel steroid co-activator of the estrogen receptor (ER), and EGF, and leucine-rich protein-1), and studies have shown the deregulation of MNAR in breast tumours and endometrial cancers, glutamic acid-, histone deacetylase 2 and MTA (metastasis-associated protein)1, leading to MAPK activation, otherwise known as PELP1 (proline-, which plays a role in E2-mediated cell cycle progression through interaction with the pRb pathway, MNAR This item specifically recognises MNAR (modulator of non-genomic activity of estrogen receptor) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
MNAR |
| Short name: |
Anti-MNAR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-MNAR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30134 |
| Gene: |
PELP1 |
More about : PELP1 |
| Long gene name: |
glutamate and leucine rich protein 1 , proline |
| Synonyms gene name: |
glutamic acid and leucine rich protein 1 , proline |
| Synonyms: |
MNAR |
| Locus: |
17p13, 2 |
| Discovery year: |
2005-11-22 |
| Entrez gene record: |
27043 |
| Pubmed identfication: |
11481323 12682072 |
| RefSeq identity: |
NM_014389 |
| Classification: |
5FMC ribosome biogenesis complex |
| Havana BLAST/BLAT: |
OTTHUMG00000177831 |