| known also as: |
Anti-RABBIT ANTI SOCS-1 (C-TERMINAL) |
| known also as: |
RABBIT ANTI SOCS-1 (C-TERMINAL) |
| known also as: |
Lapin ANTI SOCS-1 (C-TERMINAL) |
| known also as: |
SOCS-1 |
| Other names: |
JAB, JAK binding protein, JAK-binding protein, JAK-binding protein, SSI-1, STAT induced SH3 protein 1, STAT-induced STAT inhibitor 1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, Tec-interacting protein 3, Tec-interacting protein 3, cytokine-inducible SH2 protein 1, suppressor of cytokine signaling 1, suppressor of cytokine signaling 1, suppressor of cytokine signaling 1 |
| Gene name: |
SOCS-1 |
| Other gene names: |
CIS1, CISH1, JAB, JAB, SOCS-1, SOCS-1, SOCS1, SSI-1, SSI-1, SSI1, SSI1, TIP-3, TIP3, TIP3, SOCS1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Furthermore SOCS1 is involved in ubiquitin-dependent protein degradation, IL-12 and IL-15, IL-4, It acts mainly on the Janus kinase (JAK)/signal transducers and activators of transcription-3 (STAT3) pathway but also inhibits signalling by cytokines such as insulin and toll-like receptors, SOCS1 acts downstream of cytokine receptors and plays a role in the negative regulation of cytokine signalling, SOCS1 is expressed ubiquitously and at elevated levels in the spleen, a 24kDa member of the Suppressor of cytokine signalling family, plays a role in T cell activation and in the regulation of IL-6, small intestine and peripheral blood leukocytes, SOCS-1 Recognises Suppressor of cytokine signalling 1 (SOCS1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
SOCS-1 |
| Short name: |
Anti-SOCS-1 (C-TERMINAL) |
| Alternative name: |
antibody to-SOCS-1 (C-TERMINAL) |
| Identity: |
19383 |
| Gene: |
SOCS1 |
More about : SOCS1 |
| Long gene name: |
suppressor of cytokine signaling 1 |
| Synonyms: |
SOCS-1 SSI-1 JAB TIP3 Cish1 |
| Locus: |
16p13, 13 |
| Discovery year: |
2002-11-13 |
| GenBank acession: |
U88326 |
| Pubmed identfication: |
7796808 9266833 |
| Classification: |
Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129792 |