| Also known as: |
GRANZYME B |
| Other names: |
C11, C11, CTLA-1, CTLA-1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, Granzyme B, Granzyme-2, HLP, Human lymphocyte protein, Lymphocyte protease, SECT, T-cell serine protease 1-3E, T-cell serine protease 1-3E, cathepsin G-like 1, cytotoxic T-lymphocyte proteinase 2, cytotoxic T-lymphocyte-associated serine esterase 1), cytotoxic serine protease B, fragmentin 2, fragmentin-2, granzyme B, granzyme B (granzyme 2, human lymphocyte protein, granzyme B |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CCPI, CGL-1, CGL1, CGL1, CSP-B, CSPB, CSPB, CTLA1, CTLA1, CTSGL1, CTSGL1, GRB, GZMB, HLP, HLP, Lymphocyte protease, SECT, GZMB |
| Gene name synonims: |
CCPI, CGL-1, CGL1, CGL1, CSP-B, CSPB, CSPB, CTLA1, CTLA1, CTSGL1, CTSGL1, GRB, GZMB, HLP, HLP, Lymphocyte protease, SECT, GZMB |
| Other gene names: |
CCPI, CGL-1, CGL1, CGL1, CSP-B, CSPB, CSPB, CTLA1, CTLA1, CTSGL1, CTSGL1, GRB, GZMB, HLP, HLP, Lymphocyte protease, SECT, GZMB |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
GB10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death, Granzyme B plays a key role in the induction of apoptosis by CTLs, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, which is expressed within the granules of cytolytic lymphocytes (CTLs), GRANZYME B This item recognises the serine protease Granzyme B |
| Form/Appearance: |
Biotin (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Biotinylated |
| Gene target: |
GRANZYME B: |
| Short name: |
MOUSE Anti-GRANZYME B: Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
MOUSE antibody to-GRANZYME B:biotinilated (Antibody to) |
| Alternative technique: |
antibodies |