| known also as: |
Anti-RABBIT ANTI 14-3-3 TAU/THETA |
| known also as: |
RABBIT ANTI 14-3-3 TAU/THETA |
| known also as: |
Lapin ANTI 14-3-3 TAU/THETA |
| known also as: |
14-3-3 TAU/THETA |
| Gene name: |
14-3-3 TAU/THETA |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Sheep |
| Specificity and cross-reactivity: |
14-3-3 tau/theta also binds BCR/Abl, Along with COPI, Elevated levels of 14-3-3 tau/theta are observed in amyotrophic lateral sclerosis, It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple cell signalling pathways, It plays a role in cell cycle progression via interaction with p27(Kip1), Protein interactions with 14-3-3 show distinct preferences for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein, The isoform forms a complex with Hsp60 and cellular prion protein which may be involved in prion diseases, _x000D__x000D_14-3-3 tau/theta is primarily expressed in T-cells although it occurs at lower levels in the brain, _x000D__x000D_This item may not react with recombinant proteins that are not N-acetylated, bacterial effector protein Tir, cytoskeletal structure, heart, intracellular trafficking and targeting, pancreas placenta and kidneys, regulation of cell cycle progression, the theta isoform binds the GB1 RSR sequence involved in protein trafficking, transcription, yes-associated protein and the FSH receptor, 14-3-3 TAU/THETA This item recognises 14-3-3 tau/theta in all mammals |
| Form/Appearance: |
Serum (Serum - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
14-3-3 TAU/THETA |
| Short name: |
Anti-14-3-3 TAU/THETA |
| Alternative name: |
antibody to-14-3-3 Taurine/THETA |
| Identity: |
12854 |
| Gene: |
YWHAQ |
More about : YWHAQ |
| Long gene name: |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name: |
theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms: |
HS1 14-3-3 |
| Synonyms name: |
protein tau |
| Locus: |
2p25, 1 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
AF070556 |
| Entrez gene record: |
10971 |
| Pubmed identfication: |
11080204 |
| RefSeq identity: |
NM_006826 |
| Classification: |
14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000013848 |