| known also as: |
Anti-RABBIT ANTI STAT6 |
| known also as: |
RABBIT ANTI STAT6 |
| known also as: |
Lapin ANTI STAT6 |
| known also as: |
STAT6 |
| Other names: |
IL-4 Stat, STAT, Signal transducer and activator of transcription 6, interleukin-4 induced, interleukin4-induced, signal transducer and activator of transcription 6, signal transducer and activator of transcription 6, transcription factor IL-4 STAT, signal transducer and activator of transcription 6 isoform 1 |
| Gene name: |
STAT6 |
| Other gene names: |
D12S1644, IL-4-STAT, N/A, STAT6, STAT6B, STAT6C, STAT6 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD23 and IL-1Ra, IgE class switching and inflammation, It also plays an important role in Th2 differentiation, STAT6 proteins form homodimers which translocate to the nucleus, This antibody can be blocked by the control peptide, Upon activation, _x000D__x000D_STAT6 is a latent cytosolic transcription factor which becomes activated following phosphorylation by JAK1 and JAK3, _x000D__x000D_STAT6 is critical for the expression of many IL-4 and IL-13 responsive genes, in response to IL-4 and IL-13, including class II major histocompatibility molecules, STAT6 This item is specific for human STAT6 (signal transducer and activator of transcription 6) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunoprecipitation (IP) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
STAT6 |
| Short name: |
Anti-STAT6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
interleukin-4 induced (Antibody to), antibody to-signal transducer and activator on transcription 6 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
D12S1644 and IL-4-STAT and STAT6B and STAT6C, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0034097 and response to cytokine and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048295 and positive regulation of isotype switching to IgE isotypes and biological process this GO :0060443 and mammary gland morphogenesis and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :1902170 and cellular response to reactive nitrogen species and biological process, STAT6 and IDBG-42122 and ENSG00000166888 and 6778, STAT6 and IDBG-635695 and ENSBTAG00000006335 and 353105, Stat6 and IDBG-195602 and ENSMUSG00000002147 and 20852, interleukin-4 induced, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0002296 and T-helper 1 cell lineage commitment and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019903 : protein phosphatase binding and also this GO :0042802 : identical protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019903 : protein phosphatase binding, this GO :0042802 : identical protein binding, this GO :0043565 : sequence-specific DNA binding, signal transducer and activator of transcription 6 |
| Identity: |
11368 |
| Gene: |
STAT6 |
More about : STAT6 |
| Long gene name: |
signal transducer and activator of transcription 6 |
| Synonyms gene name: |
interleukin-4 induced , signal transducer and activator of transcription 6 |
| Synonyms: |
D12S1644 IL-4-STAT |
| Locus: |
12q13 |
| Discovery year: |
1995-11-09 |
| GenBank acession: |
BC005823 BQ028928 |
| Entrez gene record: |
6778 |
| Pubmed identfication: |
9605853 8085155 |
| RefSeq identity: |
NM_003153 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000171194 |