| Long name: |
FITC-linked Antibody to Breast Cancer Susceptibility Protein 2 (BRCA2) |
| Antigen: |
Breast Cancer Susceptibility Protein 2 (BRCA2) |
| Gene name: |
BRCA2, Breast Cancer Susceptibility Protein 2 (BRCA2) |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
BRCA2, This is an antibody designed to detect Breast Cancer Susceptibility Protein 2 (BRCA2) |
| Purification method: |
Antigen Affinity method, Caprylic Acid Ammonium Sulfate Precipitation, etc, The most common purification methods used in the antibody production are Affinity Chromatography |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
Breast Cancer Susceptibility Protein 2 (BRCA2) |
| Short name: |
Anti- Breast Cancer Susceptibility Protein 2 (BRCA2) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
early onset) (Antibody to), Antibody to Breast Cancer Susceptibility Protein 2 (breast cancer 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BRCA2 and IDBG-22703 and ENSG00000139618 and 675, BRCA2 and IDBG-630223 and ENSBTAG00000000988 and, BRCC2 and BROVCA2 and FACD and FAD and FAD1 and FANCD and FANCD1 and GLM3 and PNCA2, Brca2 and IDBG-209587 and ENSMUSG00000041147 and 12190, DNA-templated and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0048478 and replication fork protection and biological process this GO :0051276 and chromosome organization and biological process this GO :0051298 and centrosome duplication and biological process, early onset, gamma-tubulin binding, nuclei, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0007141 and male meiosis I and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007420 and brain development and biological process this GO :0007569 and cell aging and biological process this GO :0008283 and cell proliferation and biological process this GO :0008585 and female this GO nad development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010165 and response to X-ray and biological process this GO :0010225 and response to UV-C and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0010484 and H3 histone acetyltransferase activity and molecular function this GO :0010485 and H4 histone acetyltransferase activity and molecular function this GO :0030097 and hemopoiesis and biological process this GO :0030141 and secretory granule and cellular component this GO :0032465 and regulation of cytokinesis and biological process this GO :0033593 and BRCA2-MAGE-D1 complex and cellular component this GO :0033600 and negative regulation of mammary gland epithelial cell proliferation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043009 and chordate embryonic development and biological process this GO :0043015 and gamma-tubulin binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0045893 and positive regulation of transcription, this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000910 and cytokinesis and biological process this GO :0001556 and oocyte maturation and biological process this GO :0001833 and inner cell mass cell proliferation and biological process this GO :0002020 and protease binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0006281 and DNA repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006978 and DNA damage response, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0003697 : single-stranded DNA binding and also this GO :0005515 : protein binding and also this GO :0010484 : H3 histone acetyltransferase activity and also this GO :0010485 : H4 histone acetyltransferase activity and also this GO :0043015 : gamma-tubulin binding, this GO :0003697 : single-stranded DNA binding, this GO :0005515 : protein binding, this GO :0010484 : H3 histone acetyltransferase activity, this GO :0010485 : H4 histone acetyltransferase activity, this GO :0043015 : gamma-tubulin binding, breast cancer 2 |
| Identity: |
1101 |
| Gene: |
BRCA2 |
More about : BRCA2 |
| Long gene name: |
BRCA2, DNA repair associated |
| Synonyms gene: |
FANCD1 FACD FANCD |
| Synonyms gene name: |
Fanconi anemia, complementation group D1 breast cancer 2, early onset breast cancer 2 |
| Synonyms: |
FAD FAD1 BRCC2 XRCC11 |
| Synonyms name: |
BRCA1/BRCA2-containing complex, subunit 2 |
| Locus: |
13q13, 1 |
| Discovery year: |
1994-10-17 |
| GenBank acession: |
U43746 |
| Entrez gene record: |
675 |
| Pubmed identfication: |
8091231 7581463 15057823 |
| RefSeq identity: |
NM_000059 |
| Classification: |
Fanconi anemia complementation groups |
| Havana BLAST/BLAT: |
OTTHUMG00000017411 |
| Locus Specific Databases: |
Breast Cancer Fanconi Anaemia Mutation Database BRCA1 database at LOVD-China LOVD - Leiden Open Variation Database LOVD - Leiden Open Variation Database Fanconi anemia database LRG_293 |