| known also as: |
Anti-GOAT ANTI CRKL |
| known also as: |
Caprine ANTI CRKL |
| known also as: |
Caprinae ANTI CRKL |
| known also as: |
CRKL |
| Other names: |
Crk-like protein, N/A, crk-like protein, v-crk sarcoma virus CT10 oncogene homolog (avian)-like, crk-like protein |
| Gene name: |
CRKL |
| Other gene names: |
CRKL, N/A, N/A, CRKL |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
_x000D__x000D_CRKL is a substitute of BCR-ABL tyrosine kinase, a 33kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS-dependant manner, CRKL This item recognises CRKL |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CRKL |
| Short name: |
GOAT ANTI CRKL Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
caprine antibody to v-crk sarcoma virus CT10 oncogene homolog (avian)-like (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CRKL and IDBG-1833 and ENSG00000099942 and 1399, CRKL and IDBG-637664 and ENSBTAG00000045548 and, Crkl and IDBG-138913 and ENSMUSG00000006134 and 12929, Cytoplasm, poly(A) RNA binding, this GO :0000186 and activation of MAPKK activity and biological process this GO :0001568 and blood vessel development and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0007254 and JNK cascade and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007389 and pattern specification process and biological process this GO :0007507 and heart development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048538 and thymus development and biological process this GO :0060017 and parathyroid gland development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0044822 : poly(A) RNA binding, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0044822 : poly(A) RNA binding, v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Identity: |
2363 |
| Gene: |
CRKL |
More about : CRKL |
| Long gene name: |
CRK like proto-oncogene, adaptor protein |
| Synonyms gene name: |
v-crk avian sarcoma virus CT10 oncogene homolog-like |
| Locus: |
22q11, 21 |
| Discovery year: |
1994-09-14 |
| Entrez gene record: |
1399 |
| Pubmed identfication: |
8361759 8798523 |
| RefSeq identity: |
NM_005207 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150807 |