| known also as: |
Anti-RABBIT ANTI HUMAN PEN2 (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN PEN2 (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens PEN2 (N-TERMINAL) |
| known also as: |
PEN2 |
| Other names: |
Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, elegans), gamma-secretase subunit PEN-2, hematopoietic stem/progenitor cells protein MDS033, presenilin enhancer 2 homolog (C, gamma-secretase subunit PEN-2 |
| Gene name: |
PEN2 |
| Other gene names: |
MDS033, MSTP064, PEN-2, PEN2, PEN2, PSENEN, PSENEN |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
It is the addition of PEN2, PEN2 expression has been observed in leukocytes, The gamma secretase complex consists of nicastrin, These include Notch receptors and the beta-amyloid precursor protein which is cleaved to form amyloid beta peptide, This complex is an endoprotease that cleaves integral membrane proteins, a 12 kDa member of the PEN2 family and subunit of the gamma-secretase complex, a major component of the neuritic plaques found in Alzheimer's disease, heart and brain, kidney, liver, lung, placenta, skeletal muscle, small intestine, spleen thymus, the final stage of gamma secretase maturation that facilitates endoproteolysis of presenilin and confers proteolytic activity, the presenilin homodimers and APH1, PEN2 This item recognises Presenilin enhancer protein 2 (PEN) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
PEN2 |
| Short name: |
Anti-HUMAN PEN2 (N-TERMINAL) |
| Alternative name: |
sapiens PEN2 (N-TERMINAL), antibody to-H |
| Identity: |
30100 |
| Gene: |
PSENEN |
More about : PSENEN |
| Long gene name: |
presenilin enhancer gamma-secretase subunit |
| Synonyms gene name: |
elegans) , presenilin enhancer 2 homolog (C |
| Synonyms: |
PEN2 |
| Locus: |
19q13, 12 |
| Discovery year: |
2005-02-08 |
| GenBank acession: |
AF220053 |
| Entrez gene record: |
55851 |
| Pubmed identfication: |
12110170 12660785 |
| RefSeq identity: |
NM_172341 |
| Havana BLAST/BLAT: |
OTTHUMG00000182067 |
| Locus Specific Databases: |
LRG_222 |