| known also as: |
Anti-RABBIT ANTI HUMAN CD281 (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN CD281 (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens CD281 (N-TERMINAL) |
| known also as: |
CD281 |
| Other names: |
Toll-like receptor 1, Toll/interleukin-1 receptor-like protein, toll-like receptor 1, toll-like receptor 1, toll/interleukin-1 receptor-like protein, toll-like receptor 1 |
| Gene name: |
CD281 |
| Other gene names: |
CD281, KIAA0012, LPRS5, TIL, TIL, TIL, TLR1, rsc786, TLR1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
TLR1 can associate with TLR4 and inhibit its signalling in endothelial cells, TLR1 is co-expressed with TLR2 on monocytes and dendritic cells where they form heterodimers that can recognize peptidoglycan and bacterial lipopeptides, TLRs recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, _x000D__x000D_TLR1 can also regulate other TLR responses, also known as toll like receptor 1 (TLR1), and can associate with TLR2 to inhibit the TLR2/TLR6 mediated response to phenol-soluble modulin, and in particular triacylated lipoproteins, and serve as an important link between the innate and adaptive immune response through the production of cytokines, CD281 This item detects an epitope within the N-terminal (NT) region of CD281 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Frozen (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD281 |
| Short name: |
Anti-HUMAN CD281 (N-TERMINAL) |
| Alternative name: |
sapiens CD281 (N-TERMINAL), antibody to-H |
| Identity: |
11847 |
| Gene: |
TLR1 |
More about : TLR1 |
| Long gene name: |
toll like receptor 1 |
| Synonyms gene name: |
toll-like receptor 1 |
| Synonyms: |
rsc786 KIAA0012 CD281 |
| Locus: |
4p14 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88540 |
| Entrez gene record: |
7096 |
| Pubmed identfication: |
9435236 7584026 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000160413 |