| known also as: |
Anti-RABBIT ANTI HUMAN PACE4 |
| known also as: |
RABBIT ANTI HUMAN PACE4 |
| known also as: |
Lapin ANTI Homo sapiens PACE4 |
| known also as: |
PACE4 |
| Other names: |
Paired basic amino acid cleaving enzyme 4, Proprotein convertase subtilisin/kexin type 6, SPC4, Subtilisin-like proprotein convertase 4, Subtilisin/kexin-like protease PACE4, paired basic amino acid cleaving enzyme 4, paired basic amino acid cleaving system 4, proprotein convertase subtilisin/kexin type 6, proprotein convertase subtilisin/kexin type 6, subtilisin-like proprotein convertase 4, subtilisin/kexin-like protease PACE4, proprotein convertase subtilisin/kexin type 6 isoform a preproprotein |
| Gene name: |
PACE4 |
| Other gene names: |
PACE4, PACE4, PCSK6, SPC4, SPC4, PCSK6 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
It cleaves its substrates at their paired basic amino acid processing sites, It is thought to have a similar role in humans, PACE4 belongs to the subtilisin-like proprotein convertase family, PACE4 has been shown to increase tumor cell invasiveness, Several PACE4 substrates have been identified, _x000D__x000D_In mouse, and is a 100kD calcium dependent serine endoprotease located in the endoplasmic reticulum, and thus enhance tumor progression, converting them into their biologically active products, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor, PACE4 This item detects an epitope within the internal region of human Paired basic amino acid cleaving system 4 (PACE4) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
PACE4 |
| Short name: |
Anti-HUMAN PACE4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens PACE4 (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8569 |
| Gene: |
PCSK6 |
More about : PCSK6 |
| Long gene name: |
proprotein convertase subtilisin/kexin type 6 |
| Synonyms gene: |
PACE4 |
| Synonyms gene name: |
paired basic amino acid cleaving system 4 |
| Synonyms: |
SPC4 |
| Synonyms name: |
subtilisin-like protease subtilisin-like proprotein convertase 4 subtilisin/kexin-like protease PACE4 |
| Locus: |
15q26 |
| Discovery year: |
1992-06-05 |
| Entrez gene record: |
5046 |
| Pubmed identfication: |
1741956 |
| RefSeq identity: |
NM_002570 |
| Classification: |
Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT: |
OTTHUMG00000172097 |
| Locus Specific Databases: |
LRG_888 |