| known also as: |
Anti-GOAT ANTI HUMAN COFILIN 2 (C-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN COFILIN 2 (C-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens COFILIN 2 (C-TERMINAL) |
| known also as: |
COFILIN 2 |
| Other names: |
Cofilin, Cofilin-2, cofilin, cofilin 2 (muscle), cofilin-2, muscle isoform, muscle isoform, nemaline myopathy type 7, cofilin-2 isoform 1 |
| Other gene names: |
CFL2, N/A, NEM7, CFL2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Cofilin 2 is the major component of intranuclear and cytoplasmic actin rods, During postnatal development, It is suggested that cofilin 2 could be associated with actin filaments in muscle cells more efficiently than cofilin 1, The onset of cofilin 2 expression is coupled with terminal differentiation of muscle cells, _x000D__x000D_Cofilin 2 is expressed in developing skeletal muscle at early foetal stages through to a young postnatal stage, an 18kD protein which is involved in the regulation of actin assembly in developing myotubes through the reversible control of actin polymerization and depolymerization, cofilin 1 expression in muscle is down-regulated and cofilin 2 becomes the only isoform in mature skeletal muscle, COFILIN 2 This item detects an epitope within the C-terminal (CT) of cofilin 2 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
COFILIN 2 |
| Short name: |
GOAT ANTI HUMAN COFILIN 2 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens COFILIN 2 (C-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
1875 |
| Gene: |
CFL2 |
More about : CFL2 |
| Long gene name: |
cofilin 2 |
| Synonyms gene name: |
cofilin 2 (muscle) |
| Synonyms: |
NEM7 |
| Synonyms name: |
nemaline myopathy type 7 |
| Locus: |
14q13, 1 |
| Discovery year: |
1995-07-11 |
| GenBank acession: |
AF087867 |
| Entrez gene record: |
1073 |
| Pubmed identfication: |
8800436 |
| RefSeq identity: |
NM_138638 |
| Havana BLAST/BLAT: |
OTTHUMG00000029536 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_213 |