| known also as: |
Anti-RABBIT ANTI HUMAN CD271 |
| known also as: |
RABBIT ANTI HUMAN CD271 |
| known also as: |
Lapin ANTI Homo sapiens CD271 |
| known also as: |
CD271 |
| Other names: |
Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, NGF receptor, TNFR superfamily, Tumor necrosis factor receptor superfamily member 16, low affinity nerve growth factor receptor, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, member 16, nerve growth factor receptor, p75 ICD, p75 ICD, tumor necrosis factor receptor superfamily member 16, tumor necrosis factor receptor superfamily member 16 |
| Gene name: |
CD271 |
| Other gene names: |
CD271, Gp80-LNGFR, NGF receptor, NGFR, TNFRSF16, TNFRSF16, p75(NTR), p75NTR, NGFR |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD271 is involved in apoptosis, It is a pro-apoptotic member of the tumour necrosis factor receptor (TNFR) family and its ligands include NGF, NT3 and NT4, When signalling alone, _x000D__x000D_CD271 has been shown to interact with tropomyosin-receptor-kinase A (TrkA) forming the high-affinity NGF receptor, _x000D__x000D_Mutations and changes in CD271 expression have been implicated in various pathological diseases including Alzheimer's Disease, a transmembrane protein of 70-75kDa, brain derived growth neurotrophic factor (BDNF), cerebral oedema and retinoblastoma, constituting the low-affinity NGF receptor, neurite outgrowth during development and myelination, otherwise known as Nerve Growth Factor Receptor (NGFR), while CD271 can signal alone, CD271 This item recognises CD271 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistology - Frozen (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CD271 |
| Short name: |
Anti-HUMAN CD271 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD271 (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
7809 |
| Gene: |
NGFR |
More about : NGFR |
| Long gene name: |
nerve growth factor receptor |
| Synonyms gene name: |
member 16) , nerve growth factor receptor (TNFR superfamily |
| Synonyms: |
TNFRSF16 CD271 p75NTR |
| Synonyms name: |
low affinity nerve growth factor receptor TNFR superfamily, member 16 |
| Locus: |
17q21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M14764 |
| Entrez gene record: |
4804 |
| Pubmed identfication: |
3022937 3006050 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000161495 |