| known also as: |
Anti-RABBIT ANTI MOUSE CD254 |
| known also as: |
RABBIT ANTI Murine CD254 |
| known also as: |
Lapin ANTI Mus musculus CD254 |
| known also as: |
CD254 |
| Other names: |
ODF, OPG ligand, OPGL, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNF-related activation-induced cytokine, Tumor necrosis factor ligand superfamily member 11, member 11, osteoclast differentiation factor, osteoprotegerin ligand, receptor activator of NF-kappaB ligand, receptor activator of nuclear factor kappa B ligand, receptor activator of nuclear factor kappa-B ligand, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 11, tumor necrosis factor-related activation-induced cytokine, tumor necrosis factor ligand superfamily member 11 |
| Gene name: |
CD254 |
| Other gene names: |
Ly109l, ODF, ODF, OPG, OPGL, OPGL, Opgl, RANKL, RANKL, Rankl, TRANCE, Tnfsf11, Trance, Trance, Tnfsf11 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse |
| Specificity and cross-reactivity: |
_x000D__x000D_CD254 plays a role in the differentiation/maturation of osteoclast precursors and may act as a regulator of T lymphocytes and dendritic cell interactions, a 19, as demonstrated by its ability to augment the dendritic cell stimulation of naï, comprising the full-length of the TNF-like extracellular domain of RANKL, expressed abundantly by T lymphocytes and cells of osteoblastic origin, in a mixed lymphocyte reaction (MLR), otherwise known as sRANKL, 4kDa soluble protein and member of the TNF superfamily, CD254 This item is specific for mouse CD254, _x000D_, ve T-cell proliferation |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD254 |
| Short name: |
Anti-MOUSE CD254 |
| Alternative name: |
antibody to-MOUSE CD254 |
| Identity: |
11926 |
| Gene: |
TNFSF11 |
More about : TNFSF11 |
| Long gene name: |
tumor necrosis factor superfamily member 11 |
| Synonyms gene name: |
member 11 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
TRANCE RANKL OPGL ODF CD254 |
| Locus: |
13q14 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF013171 |
| Pubmed identfication: |
9312132 9367155 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000016807 |