| known also as: |
Anti-RABBIT ANTI HUMAN BMP-7:Biotin |
| known also as: |
RABBIT ANTI HUMAN BMP-7:Biotin |
| known also as: |
Lapin ANTI Homo sapiens BMP-7:Biotin |
| known also as: |
BMP-7 |
| Other names: |
Bone morphogenetic protein 7, Osteogenic protein 1, bone morphogenetic protein 7, bone morphogenetic protein 7, osteogenic protein 1, bone morphogenetic protein 7 |
| Gene name: |
BMP-7 |
| Other gene names: |
BMP-7, BMP7, OP-1, OP-1, OP1, BMP7 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
BMP-7 is a member of the transforming growth factor beta (TGF-B) superfamily and one of a growing number of osteogenic proteins shown to induce bone and cartilage formation, Results from research into experimental diabetic nephropathy have indicated that BMP-7 has antifibrogenic properties and appears to act as an antagonist to TGF-Beta <, Several antagonist proteins, _x000D__x000D_BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, _x000D__x000D_Studies into the properties of BMP-7 have largely focused on its role during ontogeny of the kidney, and to play an important role in developmental processes, apoptosis and morphogenesis, are responsible for modulating the signaling effects of BMPs, chordin, differentiation, gremlin and follistatin, including, including cell proliferation, noggin, owing to its prominent expression in the renal tubules, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways, thereby preventing activation, through the binding and blocking of receptor ligands, (3-4)<, /sup>, BMP-7 This item recognizes the disulphide-linked homodimeric cysteine knot protein known as human Bone Morphogenetic Protein 7 (BMP-7) or Osteogenic protein 1 (OP-1), sup> |
| Form/Appearance: |
Biotin (Purified IgG conjugated to Biotin - lyophilised) |
| Concentration: |
1 miligram per 1 mililiter after reconstitution, IgG concentration 0 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| Gene target: |
BMP-7: |
| Short name: |
Anti-HUMAN BMP-7: |
| Label: |
Biotin |
| Alternative name: |
sapiens BMP-7:biotinilated, antibody to-H |