| Long name: |
Polyclonal Antibody to Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) |
| Antigen: |
Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) |
| Other names: |
SHP-2 interacting transmembrane adaptor protein, SHP2 interacting transmembrane adaptor, SHP2-interacting transmembrane adapter protein, SHP2-interacting transmembrane adapter protein, SHP2-interacting transmembrane adaptor protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1, gp30/40, gp30/40, signaling threshold regulating transmembrane adaptor 1, signaling threshold-regulating transmembrane adapter 1, suppression inducing transmembrane adaptor 1, suppression-inducing transmembrane adapter 1, signaling threshold-regulating transmembrane adapter 1 |
| Gene name: |
SIT1, Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) |
| Gene synonims: |
RP11-331F9, SIT, SIT, SIT-R, SIT1, 5, SIT1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, It has been selected for its ability to recognize SIT1 in immunohistochemical staining andwestern blotting, SIT1, The antibody is a rabbit polyclonal antibody raised against SIT1, This is an antibody designed to detect Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Description: |
By understanding cell signaling, Errors in cellular information processing are responsible for diseases such as cancer, The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, and diabetes, and immunity as well as normal tissue homeostasis, artificial tissues may be created, autoimmunity, diseases may be treated effectively and, theoretically, tissue repair, Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions |
| Gene target: |
Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) |
| Short name: |
Anti- Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Antibody to Signaling Threshold Regulating Transmembrane Adaptor 1 (signaling threshold regulating transmembrane adaptor 1) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, SH2 domain binding, SIT1 and IDBG-62762 and ENSG00000137078 and 27240, SIT1 and IDBG-633050 and ENSBTAG00000011411 and 512027, Sit1 and IDBG-141175 and ENSMUSG00000028460 and 54390, this GO :0002376 and immune system process and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0019900 and kinase binding and molecular function this GO :0042169 and SH2 domain binding and molecular function this GO :0050863 and regulation of T cell activation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019900 : kinase binding and also this GO :0042169 : SH2 domain binding, this GO :0019900 : kinase binding, this GO :0042169 : SH2 domain binding, signaling threshold regulating transmembrane adaptor 1 |
| Identity: |
17710 |
| Gene: |
SIT1 |
More about : SIT1 |
| Long gene name: |
signaling threshold regulating transmembrane adaptor 1 |
| Synonyms gene name: |
suppression inducing transmembrane adaptor 1 |
| Synonyms: |
SIT |
| Synonyms name: |
SHP2 interacting transmembrane adaptor |
| Locus: |
9p13, 3 |
| Discovery year: |
2005-04-25 |
| Entrez gene record: |
27240 |
| Pubmed identfication: |
11491537 10209036 |
| RefSeq identity: |
NM_014450 |
| Havana BLAST/BLAT: |
OTTHUMG00000019867 |