| Long name: |
SIGLEC9 Primary Polyclonal Antibody |
| Also known as: |
SIGLEC9 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SIGLEC9 |
| Specificity: |
This is a highly specific antibody against SIGLEC9 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIGLEC9 |
| Gene ID number: |
27180 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is highly expressed in peripheral blood leukocytes (but not eosinophils), Siglec-1 mediates local cell-cell interactions in lymphoid tissues and can be detected at contact points of macrophages with other macrophages, Siglec-7, Siglec-8, Siglec-9 is closely homologous to Siglec-7, The common sialic acids of mammalian cells are N-acetyl-neuraminic acid (Neu5Ac) and N-glycolyl-neuraminic acid (Neu5Gc), The sialic acid-binding immunoglobulin superfamily lectins, a type I membrane protein, are immunoglobulin superfamily members recognizing sialylated ligands, basophils and mast cells, bone marrow, but not in parenchymatous cells, designated siglecs or sialoadhesins, highly expressed in monocytes and resident blood cells, is selectively expressed on human eosinophils, liver, mediates inhibition of natural killer cell cytotoxicity, placenta and spleen, sinus-lining cells and reticulum cells, the gene encoding it maps to chromosome 19q13, where it regulates their function and survival, 41 in humans, Two families of mammalian lectin-like adhesion molecules bind glycoconjugate ligands in a sialic acid-dependent manner: the selectins and the sialoadhesins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CDw329, OB binding protein like, OBBP LIKE, Protein FOAP 9, Protein FOAP-9, SIGL9_HUMAN, SIGLEC9, Sialic acid-binding Ig-like lectin 9, Sialic acid-binding immunoglobulin like lectin 9, Siglec 9, Siglec-9, sialic acid binding Ig like lectin 9, CD329 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SIGLEC9 |
| Short name: |
SIGLEC9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sialic acid binding Ig-like lectin 9 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, SIGLEC9 and IDBG-65664 and ENSG00000129450 and 27180, carbohydrate binding, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0045087 and innate immune response and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0030246 : carbohydrate binding, this GO :0030246 : carbohydrate binding, sialic acid binding Ig-like lectin 9 |
| Identity: |
10878 |
| Gene: |
SIGLEC9 |
More about : SIGLEC9 |
| Long gene name: |
sialic acid binding Ig like lectin 9 |
| Synonyms gene name: |
sialic acid binding Ig-like lectin 9 |
| Synonyms: |
CD329 |
| Locus: |
19q13, 3-q13, 4 |
| Discovery year: |
2000-03-29 |
| GenBank acession: |
AF135027 |
| Entrez gene record: |
27180 |
| Pubmed identfication: |
10903842 |
| RefSeq identity: |
NM_014441 |
| Classification: |
CD molecules Sialic acid binding Ig like lectins V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182894 |