| Long name: |
FITC Conjugated, MYLIP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MYLIP |
| Specificity: |
This is a highly specific antibody against MYLIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
65-103/445 |
| Subcellular location: |
Cell membrane |
| Source: |
KLH conjugated synthetic peptide derived from human MYLIP |
| Gene ID number: |
29116 |
| Swiss Prot: |
Q8WY64 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activity depends on E2 enzymes of the UBE2D family, Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR, LDLR, Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth, VLDLR and LRP8, E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MIR IDOL |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MYLIP Conjugated |
| Short name: |
FITC Conjugated, MYLIP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, MYLIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21155 |
| Gene: |
MYLIP |
More about : MYLIP |
| Long gene name: |
myosin regulatory light chain interacting protein |
| Synonyms name: |
E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor |
| Locus: |
6p22, 3 |
| Discovery year: |
2003-11-26 |
| GenBank acession: |
AF187016 |
| Entrez gene record: |
29116 |
| Pubmed identfication: |
10593918 11162443 19688294 |
| RefSeq identity: |
NM_013262 |
| Classification: |
FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000016405 |