| Long name: |
Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 2 (bACE2) |
| Antigen: |
Beta-Site APP Cleaving Enzyme 2 (bACE2) |
| Other names: |
56 kDa aspartic-like protease, ASP1, Asp 1, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-secretase 2, Beta-site APP cleaving enzyme 2, Beta-site amyloid precursor protein cleaving enzyme 2, DRAP, Down region aspartic protease, Down syndrome region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, aspartyl protease 1, beta-secretase 2, beta-site APP-cleaving enzyme 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, memapsin-1, membrane-associated aspartic protease 1, theta-secretase, transmembrane aspartic proteinase Asp1, Beta-site APP-cleaving enzyme 2 |
| Gene name: |
bACE2, Beta-Site APP Cleaving Enzyme 2 (bACE2) |
| Gene synonims: |
AEPLC, AEPLC, ALP56, ALP56, ASP1, ASP1, ASP21, ASP21, Asp 1, BACE2, BAE2, Beta-site APP cleaving enzyme 2, CDA13, CEAP1, DRAP, DRAP, BACE2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, It has been selected for its ability to recognize bACE2 in immunohistochemical staining andwestern blotting, bACE2, The antibody is a rabbit polyclonal antibody raised against bACE2, This is an antibody designed to detect Beta-Site APP Cleaving Enzyme 2 (bACE2) |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Description: |
Activating enzymes will cut off the domain that is biological active to become functional, If the substrate is DNA they are called restriction enzymes, Enzymes are cleaving the substrate |
| Gene target: |
Beta-Site APP Cleaving 2 (bACE2) |
| Short name: |
Anti- Beta-Site APP Cleaving Enzyme 2 (bACE2) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, enzymes, Antibody |
| Alternative name: |
Antibody to b-Site amyloid beta (A4) precursor protein Cleaving Enzyme 2 (bACE2) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, APP and IDBG-630293 and ENSBTAG00000017753 and 280722, App and IDBG-172954 and ENSMUSG00000022892 and 11820, growth factor receptor binding, leucine rich repeat containing receptor signaling pathway and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043197 and dendritic spine and cellular component this GO :0043198 and dendritic shaft and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043393 and regulation of protein binding and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045177 and apical part of cell and cellular component this GO :0045202 and synapse and cellular component this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046914 and transition metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048669 and collateral sprouting in absence of injury and biological process this GO :0050803 and regulation of synapse structure and activity and biological process this GO :0050885 and neuromuscular process controlling balance and biological process this GO :0051124 and synaptic growth at neuromuscular junction and biological process this GO :0051233 and spindle midzone and cellular component this GO :0051402 and neuron apoptotic process and biological process this GO :0051425 and PTB domain binding and molecular function this GO :0051563 and smooth endoplasmic reticulum calcium ion homeostasis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070851 and growth factor receptor binding and molecular function, nuclei, this GO :0000085 and mitotic G2 phase and biological process this GO :0001967 and suckling behavior and biological process this GO :0002576 and platelet degranulation and biological process this GO :0003677 and DNA binding and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005641 and nuclear envelope lumen and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006378 and mRNA polyadenylation and biological process this GO :0006417 and regulation of translation and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006878 and cellular copper ion homeostasis and biological process this GO :0006897 and endocytosis and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007155 and cell adhesion and biological process this GO :0007176 and regulation of epidermal growth factor-activated receptor activity and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007409 and axonogenesis and biological process this GO :0007596 and blood coagulation and biological process this GO :0007617 and mating behavior and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008088 and axon car this GO transport and biological process this GO :0008201 and heparin binding and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008344 and adult locomotory behavior and biological process this GO :0008542 and visual learning and biological process this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0010952 and positive regulation of peptidase activity and biological process this GO :0010971 and positive regulation of G2/M transition of mitotic cell cycle and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016199 and axon midline choice point recognition and biological process this GO :0016322 and neuron remodeling and biological process this GO :0016358 and dendrite development and biological process this GO :0016504 and peptidase activator activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030134 and ER to this GO lgi transport vesicle and cellular component this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030424 and axon and cellular component this GO :0030900 and forebrain development and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031175 and neuron projection development and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031594 and neuromuscular junction and cellular component this GO :0033130 and acetylcholine receptor binding and molecular function this GO :0035235 and ionotropic glutamate receptor signaling pathway and biological process this GO :0035253 and ciliary rootlet and cellular component this GO :0035872 and nucleotide-binding domain, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0016504 : peptidase activator activity and also this GO :0019899 : enzyme binding and also this GO :0033130 : acetylcholine receptor binding and also this GO :0042802 : identical protein binding and also this GO :0046914 : transition metal ion binding and also this GO :0051425 : PTB domain binding and also this GO :0070851 : growth factor receptor binding, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0008201 : heparin binding, this GO :0016504 : peptidase activator activity, this GO :0019899 : enzyme binding, this GO :0033130 : acetylcholine receptor binding, this GO :0042802 : identical protein binding, this GO :0046914 : transition metal ion binding, this GO :0051425 : PTB domain binding, this GO :0070851 : growth factor receptor binding, amyloid beta (A4) precursor protein |
| Identity: |
620 |
| Gene: |
APP |
More about : APP |
| Long gene name: |
amyloid beta precursor protein |
| Synonyms gene: |
AD1 |
| Synonyms gene name: |
Alzheimer disease amyloid beta (A4) precursor protein |
| Synonyms name: |
peptidase nexin-II |
| Locus: |
21q21, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M15533 |
| Entrez gene record: |
351 |
| Pubmed identfication: |
1679289 |
| RefSeq identity: |
NM_000484 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000078438 |
| Locus Specific Databases: |
Alzheimer Disease &, Frontotemporal Dementia Mutation Database |