| Long name: |
ALEXA FLUOR 350 Conjugated, DERP6 Polyclonal Antibody |
| Also known as: |
Anti-DERP6 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DERP6 |
| Specificity: |
This is a highly specific antibody against DERP6 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DERP6/C17orf81 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BRCA1 is directly involved in DNA repair, DERP6 is thought to be involved in p53-mediated transcriptional regulation, Expressed ubiquitously with highest expression in liver, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding DERP6 maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, brain and skeletal muscle, colon, heart, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms, namely, p53 and BRCA1, prostate gland and fallopian tubes, testis, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, DERP6 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
DERP6 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
DERP6 |
| Short name: |
DERP6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, DERP6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30617 |
| Gene: |
ELP5 |
More about : ELP5 |
| Long gene name: |
elongator acetyltransferase complex subunit 5 |
| Synonyms gene: |
C17orf81 |
| Synonyms gene name: |
chromosome 17 open reading frame 81 |
| Synonyms name: |
dermal papilla derived protein 6 S-phase 2 protein |
| Locus: |
17p13, 1 |
| Discovery year: |
2006-02-13 |
| GenBank acession: |
BC002762 |
| Entrez gene record: |
23587 |
| Pubmed identfication: |
22854966 |
| RefSeq identity: |
NM_015362 |
| Classification: |
Elongator acetyltransferase complex |
| Havana BLAST/BLAT: |
OTTHUMG00000177974 |