| Long name: |
ALAS-E Primary Polyclonal Antibody |
| Also known as: |
ALAS-E PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ALAS-E |
| Specificity: |
This is a highly specific antibody against ALAS-E |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALAS2/ALAS-E |
| Gene ID number: |
212 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ALAS-E, ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells, NF-E2 and EKLF, Since the ALAS gene maps to the X chromosome, Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H, The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, The erythroid-specific isoenzyme, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver, 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
5 aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5-aminolevulinate synthase 2, 5-aminolevulinate synthase 2, 5-aminolevulinic acid synthase, ALAS, ALAS, ALAS E, ALAS E, ALASE, ALASE, ANH1, ANH1, ASB, Alas 2, Aminolevulinate, Aminolevulinic acid synthase 2, Delta ALA synthase 2, Delta ALA synthetase, Delta aminolevulinate synthase, Delta aminolevulinate synthase, Delta aminolevulinate synthase 2, Erythroid specic ALAS, FLJ93603, XLDPP, XLSA, XLSA, delta-, erythroid, erythroid, erythroid-specic, mitochondrial, synthase 2, 5-aminolevulinate synthase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ALAS-E |
| Short name: |
ALAS-E Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ALAS-E (Antibody to) |
| Alternative technique: |
antibodies |