| Long name: |
RNF125 Primary Polyclonal Antibody |
| Also known as: |
RNF125 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RNF125 |
| Specificity: |
This is a highly specific antibody against RNF125 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRAC1/RNF125 |
| Gene ID number: |
9611 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Expressed predominantly in lymphoid tissues such as spleen, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, TRAC-1 (T-cell RING activation protein 1), TRAC-1 has been found to inhibit pathogen-induced cytokine production and down-regulates HIV replication, also known as RNF125 (ring finger protein 125) or E3 ubiquitin-protein ligase RNF125, is a 232 amino acid novel E3 ubiquitin ligase that functions as a positive regulator in the T-cell receptor signaling pathway, thymus and bone marrow, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E3 ubiquitin protein ligase RNF125, RN125_HUMAN, RNF 125, Ring finger protein 125, T cell ring protein identied in activation screen, TRAC 1, TRAC1, T cell RING activation protein 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF125 |
| Short name: |
RNF125 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RNF125 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21150 |
| Gene: |
RNF125 |
More about : RNF125 |
| Long gene name: |
ring finger protein 125 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring finger protein 125 |
| Synonyms: |
FLJ20456 |
| Locus: |
18q12, 1 |
| Discovery year: |
2003-05-21 |
| GenBank acession: |
AK000463 |
| Entrez gene record: |
54941 |
| RefSeq identity: |
NM_017831 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132266 |