| Long name: |
COPS2 Primary Polyclonal Antibody |
| Also known as: |
COPS2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
COPS2 |
| Specificity: |
This is a highly specific antibody against COPS2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human COPS2/TRIP15 |
| Gene ID number: |
1447 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CSA or DDB2, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, ITPK1 and IRF8/ICSBP, IkappaBalpha/NFKBIA, Involved in early stage of neuronal differentiation via its interaction with NIF3L1, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, The complex is also involved in phosphorylation of p53/TP53, a complex involved in various cellular and developmental processes, c-jun/JUN, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, possibly via its association with CK2 and PKD kinases, respectively, Essential component of the COP9 signalosome complex (CSN) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Alien homolog, COP 9, COP9, COP9 constitutive photomorphogenic homolog subunit 2, COP9 signalosome complex subunit 2, COPS 2, CSN2, CSN2_HUMAN, Cops2, JAB1 containing signalosome subunit 2, JAB1-containing signalosome subunit 2, SGN 2, SGN2, Signalosome subunit 2, TR-interacting protein 15, TRIP 15, TRIP-15, Thyroid Hormone Receptor Interactor 15, Thyroid Hormone Receptor Interactor15, Thyroid receptor-interacting protein 15, ALIEN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
COPS2 |
| Short name: |
COPS2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
COPS2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30747 |
| Gene: |
COPS2 |
More about : COPS2 |
| Long gene name: |
COP9 signalosome subunit 2 |
| Synonyms gene name: |
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) |
| Synonyms: |
TRIP15 ALIEN CSN2 |
| Locus: |
15q21, 2 |
| Discovery year: |
2004-11-03 |
| GenBank acession: |
AF212227 |
| Entrez gene record: |
9318 |
| Pubmed identfication: |
7776974 9535219 |
| RefSeq identity: |
NM_004236 |
| Classification: |
COP9 signalosome |
| Havana BLAST/BLAT: |
OTTHUMG00000172324 |