| Long name: |
Biotin Conjugated, NOB1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NOB1 |
| Specificity: |
This is a highly specific antibody against NOB1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NOB1 |
| Gene ID number: |
28987 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Expressed in placenta, NOB1P contains a PIN domain, NOB1P interacts with Rent2, NOB1P is essential for the synthesis of 40S ribosome subunits, Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, endothelial cells, liver and lung, spleen, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons, NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NOB1P ART-4 MST158 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NOB1 Conjugated |
| Short name: |
Conjugated, NOB1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, NOB1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29540 |
| Gene: |
NOB1 |
More about : NOB1 |
| Long gene name: |
NIN1/PSMD8 binding protein 1 homolog |
| Synonyms gene: |
PSMD8BP1 |
| Synonyms gene name: |
PSMD8 binding protein 1 NIN1/RPN12 binding protein 1 homolog (S, cerevisiae) NIN1/RPN12 binding protein 1 homolog |
| Synonyms name: |
nin one binding protein |
| Locus: |
16q22, 1 |
| Discovery year: |
2006-02-27 |
| GenBank acession: |
AB026125 |
| Entrez gene record: |
28987 |
| Pubmed identfication: |
16172919 |
| RefSeq identity: |
NM_014062 |
| Havana BLAST/BLAT: |
OTTHUMG00000137576 |